Results 281 to 290 of about 111,099 (385)
Prognostic factors in Fournier gangrene.
J. Ruiz-Tovar, L. Córdoba, J. M. Devesa
semanticscholar +1 more source
Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla+16 more
wiley +1 more source
Gluteal ischemic gangrene due to chronic aortoiliac occlusive disease. [PDF]
Pitros C+5 more
europepmc +1 more source
Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang+11 more
wiley +1 more source
Effectiveness of quality and quantity mononuclear cells for enhancing wound healing in diabetic ischemic limb animal model. [PDF]
Sriphan P+10 more
europepmc +1 more source
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
wiley +1 more source
The clinical significance and management of finger necrosis due to cobra bite in Vietnam. [PDF]
Nam ĐP+4 more
europepmc +1 more source
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho+7 more
wiley +1 more source
Comments on "Case report on Clostridium perfringens-induced gas gangrene following an intramuscular injection: A stark reminder of injection-associated risks". [PDF]
Ghezel A, Arfaee CS.
europepmc +1 more source