Results 31 to 40 of about 4,731 (267)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Beyond Gang Truces and Mano Dura Policies: Towards Substitutive Security Governance in Latin America
Stability : International Journal of Security and Development, 2016 With responses to urban violence receiving increasing academic attention, the literature on anti-gang efforts in Latin America has focused mainly on coercive 'mano dura' policies and cooperative gang truces.
Moritz Schuberth
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
مجلة العلوم و آفاق المعارفThis study sought to examine the role of social media platforms, specifically Facebook, in the efforts to combat and control street gangs in Algeria.
rym fatiha Kaddouri
doaj +1 more source
The effect of controlling organised crime on homicidal violence in Cali (Colombia)
Revista CIDOB d'Afers Internacionals, 2017 Since 1993, when the System of Surveillance of Deaths of External Causes (SVMCE, in its Spanish acronym) was established – today the Security Observatory – a reliable record of homicides has existed in Cali which has allowed the control of organised ...
Andrés Fandiño-Losada +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Genealogy, 2022 Background: The criminalisation of drill music, a rap-based genre, is a recent chapter in a long history of policing “Black” music. The association of drill and other rap music with “gang” violence has a direct impact on the treatment of Black boys and ...
Beth Hall, Roxanne Khan, Mike Eslea
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Resistência Urbana e Ativismo Social na Praia: O caso da “Korrenti di Ativiztas”
Cadernos de Estudos Africanos, 2016 The essay aims to grasp a current phenomenon of the reality of Praia, capital city of the Cape-Verdean archipelago. Socio-economical, political and urban changes of the context have concurred with the birth of new social actors, in particular the urban ...
Silvia Stefani
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source