Cytotoxic and N-Acetyltransferase Inhibitory Meroterpenoids from Ganoderma cochlear [PDF]
Seven compounds, including two pairs of new meroterpenoids, (+)- and (−)-gancochlearol C (1), (+)- and (−)-cochlearoid Q (3), and a new meroterpenoid gancochlearol D (2), together with four known meroterpenoids were isolated from the aqueous ...
Li-Zhi Cheng +5 more
doaj +5 more sources
Terminal Cyclohexane-Type Meroterpenoids from the Fruiting Bodies of Ganoderma cochlear [PDF]
Eleven new cyclohexane-type meroterpenoids (1, 3–5, 7, 8, 11–15) and four known similar meroterpenoids (2, 6, 9, and 10) were isolated from Ganoderma cochlear.
Fu-Ying Qin +7 more
doaj +4 more sources
2,5-Dihydroxyphenylethanone: an anti-melanogenic bioactive compound isolated from Ganoderma cochlear [PDF]
2,5-dihydroxyacetophenone, a natural product from the fruiting bodies of Ganoderma cochlear, can effectively and safely inhibit the production of melanin in zebrafish model.
Meng Ning +4 more
doaj +4 more sources
Total Synthesis of (+)‐Cochlearol B by an Approach Based on a Catellani Reaction and Visible‐Light‐Enabled [2+2] Cycloaddition** [PDF]
A 14‐step approach to (+)‐cochlearol B is reported. The strategy involves an organocatalytic Kabbe condensation, Catellani reaction, and visible‐light‐mediated [2+2] cycloaddition to rapidly access the core of this natural product. Careful design and tuning of the Catellani and photocycloaddition reactions proved crucial in overcoming undesired ...
Alistair D. Richardson +4 more
wiley +3 more sources
Meroterpenoid Dimers from Ganoderma Mushrooms and Their Biological Activities Against Triple Negative Breast Cancer Cells [PDF]
(±)-Dimercochlearlactones A−J (1–10), ten pairs of novel meroterpenoid dimers and one known spirocochlealactone A (11), were isolated from Ganoderma mushrooms.
Fu-Ying Qin +4 more
doaj +2 more sources
Effects and Mechanism of Ganoderma lucidum Polysaccharides in the Treatment of Diabetic Nephropathy in Streptozotocin‐Induced Diabetic Rats [PDF]
Ganoderma lucidum polysaccharides (GLP) have renal protection effect but there was no study on the diabetic nephropathy. This study was designed to investigate its effect and mechanism using a diabetic rat model induced by streptozotocin (50 mg/kg, i.p.). The diabetic rats were treated with GLP (300 mg/kg/day) for 10 weeks.
Yu Hu +10 more
wiley +2 more sources
A Ganoderma-Derived Compound Exerts Inhibitory Effect Through Formyl Peptide Receptor 2 [PDF]
Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) widely expressed in neutrophils and other phagocytes. FPRs play important roles in host defense, inflammation, and the pathogenesis of infectious and inflammatory diseases.
Huirong Wang +10 more
doaj +2 more sources
A Review of Bioactive Components and Pharmacological Effects of Ganoderma lucidum [PDF]
The active substances and medicinal effects of the medicinal mushroom Ganoderma lucidum were reviewed. ABSTRACT Ganoderma lucidum, a distinguished traditional medicinal herb, has long been recognized for its purported benefits in promoting physical well‐being, enhancing stamina, and boosting vitality.
Sizhu Ren +5 more
wiley +2 more sources
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda +5 more
wiley +2 more sources
The meroterpenoids fornicin A (1), ganodercin D (3), and fornicin D (2), found in mushrooms of the Ganoderma genus, have been prepared in a concise and divergent synthesis route, starting from readily accessible building blocks. Abstract The meroterpenoids fornicin A, fornicin D, and ganodercin D, found in mushrooms of the Ganoderma genus, have been ...
Daan V. Bunt +2 more
wiley +1 more source

