Results 211 to 220 of about 4,461,069 (318)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Time-dependent diffusion MRI: clinical potential in renal transplantation. [PDF]

EBioMedicine
Pasini S, Perico N, Caroli A.
europepmc   +1 more source

Sensitivity of direct canopy gap fraction retrieval from airborne waveform lidar to topography and survey characteristics

, 2014
X. Chen, M. Disney, Philip Lewis, J. Armston, J. Han, J. Li   +5 more
semanticscholar   +1 more source

Gap between guidelines and clinical practice in heart failure with reduced ejection fraction: Results from TSOC‐HFrEF registry

Journal of the Chinese Medical Association, 2017
Hung-Yu Chang, Chun-Chieh Wang, Jeng Wei, Chong-Yi Chang, Y. Chuang, Chien-Long Huang, E. Chong, Jiunn-lee Lin, G. Mar, Kuei‐Chuan Chan, J. Kuo, Ji-Hung Wang, Zhih-Cherng Chen, W. Tseng, W. Cherng, W. Yin   +15 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Effect of Fabric Topology and Axial Yarn Condition on the Compressive Properties of 3D Stepwise Rotary Braided Composites. [PDF]

Materials (Basel)
Mei H, Sun L, Yang R, Zhang Q, Guo Y, Han Z.   +5 more
europepmc   +1 more source

Anion Gap as a Determinant of Ionized Fraction of Divalent Cations in Hemodialysis Patients.

American Society of Nephrology. Clinical Journal, 2017
Y. Sakaguchi, T. Hamano, Keiichi Kubota, Tatsufumi Oka, Satoshi Yamaguchi, Ayumi Matsumoto, Nobuhiro Hashimoto, Daisuke Mori, Yasue Obi, I. Matsui, Y. Isaka   +10 more
semanticscholar   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Ground state and dynamics of one-dimensional quantum droplets. [PDF]

Sci Rep
Lai GY, Hsueh CH, Wu WC.
europepmc   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source