A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Advanced Science, EarlyView.Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Talking Trash: Valuing Household Preferences for Garbage and Recycling Services Bundles Using a Discrete Choice Experiment [PDF]
Facing increasing costs for tipping fees and worker salaries, many smaller municipalities have begun to explore ways to adopt mechanized pay-as-you throw container garbage collection and changes to the basket of currently provided services, such as the ...
Boyer, Tracy A.
core +1 more source
Garbage Collection in a Very Large Address Space [PDF]
, 1975 This research was done at the Artificial Intelligence Laboratory of the Massachusetts Institute of Technology and was supported by the Office of Naval Research under contract number N00014-75-C-0522.The address space is broken into areas that can be ...
Bishop, Peter B.
core
Collecting Garbage on the Blockchain
Proceedings of the 15th ACM SIGPLAN International Workshop on Virtual Machines and Intermediate Languages, 2023 Luc Bläser +5 more
openaire +1 more source
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease
Advanced Science, EarlyView.ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan +17 more
wiley +1 more source
Garbage and Recycling in Communities with Curbside Recycling and Unit-Based Pricing [PDF]
This paper estimates the impact of a user fee and a curbside recycling program on garbage and recycling amounts, allowing for the possibility of endogenous policy choices.
Don Fullerton, Thomas C. Kinnaman
core
NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
Advanced Science, EarlyView.This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Animal Protection System Cats and Dogs Approaching The Substance With The Mini Computer
CHIPSETLitter bins that do not have lids, as well as the time span of garbage collection, especially when garbage is accumulating, can attract animals to enter the bin, some of the animal patterns are to carry garbage out of the bin, so that it can be consumed
Shafira Aulia Ramadhani +3 more
doaj +1 more source
System Description for a Scalable, Fault-Tolerant, Distributed Garbage Collector
, 2002 We describe an efficient and fault-tolerant algorithm for distributed cyclic garbage collection. The algorithm imposes few requirements on the local machines and allows for flexibility in the choice of local collector and distributed acyclic garbage ...
Allen, N., Terriberry, T.
core +2 more sources
Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids
Advanced Science, EarlyView.Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang +12 more
wiley +1 more source