Results 151 to 160 of about 3,035,782 (282)

Teaching and evolution in surgical planning of robotic partial nephrectomy with 3D printing models. [PDF]

open access: yesJ Robot Surg
Loizaga Iriarte A   +12 more
europepmc   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

open access: yesAdvanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao   +6 more
wiley   +1 more source

Technology and Dementia Preconference. [PDF]

open access: yesAlzheimers Dement
Valdez MS   +20 more
europepmc   +2 more sources

Super Time‐Resolved Tomography

open access: yesAdvanced Science, EarlyView.
A super time‐resolved tomography (STRT) approach is presented to reconstruct 4D X‐ray movies with an order‐of‐magnitude improvement in temporal resolution without sacrificing spatial resolution. By leveraging a physics‐informed deep learning algorithm that shares spatiotemporal features, STRT achieves high‐fidelity 3D reconstructions from sparse‐view ...
Zhe Hu   +6 more
wiley   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

open access: yesAdvanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli   +16 more
wiley   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

Correction: A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: Unveiling a novel virulence factor. [PDF]

open access: yesPLoS Pathog
Volkening JD   +9 more
europepmc   +1 more source

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