Results 51 to 60 of about 4,450,726 (377)
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
European Psychiatry, 2022 Introduction Depression as a public health concern highlights the importance of prevention. The nature of the disease is complex, linked to numerous biopsychosocial factors.
R. Gomes +3 more
doaj +1 more source
, 2015 The most important concept in Book I of Tristan Garcia’s Forme et objet: Un traité des choses is per-haps without importance, “n’importe quoi” (“anything”).1 In an ordinary, exclamative sense, the expression “c’est n’importe quoi!” may translate as “that’s bullshit!” or “that’s rubbish!” and so on. In this sense, “n’importe quoi” is close to “nothing.”
Mark Allan Ohm, Jon Cogburn
openaire +1 more source
Book Review: Mejor Dicho [PDF]
, 1996 Review of Garcia, Carmen and Emily Spinelli. Mejor Dicho. Lexington, MA: D.C. Heath and Company, 1995, ISBN 066928906X (pbk).
Lee, Lina
core +1 more source
Specific interaction of citrate with bis(fluorophoric) bibrachial lariat aza-crown in comparison with the other components of the Krebs cycle [PDF]
, 2006 Clares Garcia, M. Paz, M.Paz.Clares@uv.es ; Garcia-España Monsonis, Enrique, Enrique.Garcia-Es@uv.es ; Soriano Soto, Concepcion, Concepcion.Soriano@uv.es ; Tejero Toquero, Roberto, Roberto.Tejero@uv ...
A. Jorge Parola +31 more
core +2 more sources
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Apathy - where do we find it and how to treat
European Psychiatry, 2022 Introduction Although defined heterogeneously within the literature apathy is classified as a multidimensional deficit with emotional, behavioral, and cognitive domains in which there is a decrease in self-motivated/goal-directed activity.
R. Gomes +3 more
doaj +1 more source
University Scholar Series: Alejandro Garcia [PDF]
, 2012 Collaborating with DreamWorks On April 25, 2012 Professor Alejandro Garcia spoke in the University Scholar Series hosted by Provost Ellen Junn at the Dr. Martin Luther King, Jr. Library.
Garcia, Alejandro
core +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
[Review of] Mario T. Garcfa, Desert Immigrants: The Mexicans of El Paso, 1880- 1920 [PDF]
, 1982 Mario T. Garcia\u27s Desert Immigrants documents and analyzes the growth of the border city of El Paso, Texas. The transformation of El Paso from a small crossroads community between Mexico and the U.S.
Rodriguez, Joe
core +1 more source