Results 81 to 90 of about 17,432 (228)

The Alzheimer's Disease Gene SORL1 Regulates Lysosome Function in Human Microglia

open access: yesGlia, Volume 73, Issue 7, Page 1329-1348, July 2025.
Main Points The AD gene SORL1 is important for maintaining lysosomal homeostasis in microglia. SORL1 KO hiPSC‐derived microglia show mis‐trafficking of lysosomal enzymes, impaired lysosomal degradation and exocytosis, and changes in neuroimmune responses.
Swati Mishra   +6 more
wiley   +1 more source

Caveolin‐1 Regulates Parathyroid Hormone (PTH)‐Related Protein (PTHrP) Actions on PTH Receptor Type 1 in Bone Cells

open access: yesJournal of Cellular Physiology, Volume 240, Issue 7, July 2025.
Caveolin1 interacts with PTH1R at membrane‐bound microdomains delaying receptor internalization, promoting cAMP signaling over calcium and ERK1/2 kinase pathways, and regulating bone formation and bone remodeling gene expression upon agonist stimulation in osteoblastic cells.
Sara Heredero‐Jiménez   +7 more
wiley   +1 more source

Protágoras y la (im)posibilidad de la contradicción

open access: yesDaimon, 2018
En este trabajo aporto nuevos argumentos para mostrar que Protágoras no defendió que contradecir fuera imposible. En primer lugar, desarrollo un análisis crítico de Eutidemo 286b8-c4 (DK 80 A 19), único testimonio donde el sofista es aparentemente ...
Mariana Gardella
doaj  

Expanders are counterexamples to the coarse $p$-Baum-Connes conjecture

open access: yes, 2018
We show that certain expanders are counterexamples to the coarse $p$-Baum-Connes conjecture.Comment: 19 ...
Chung, Yeong Chyuan, Nowak, Piotr W.
core  

Phenotypic and genetic spectrum of SCN8A‐related disorders, treatment options, and outcomes

open access: yesEpilepsia, 2019
Pathogenic variants in SCN8A have originally been described in patients with developmental and epileptic encephalopathy (DEE). However, recent studies have shown that SCN8A variants can be associated with a broader phenotypic spectrum, including the ...
E. Gardella, R. Møller
semanticscholar   +1 more source

Accompagner sans fin

open access: yesSociologies, 2016
In a context of structural precariousness, has gradually developed beside a helping relationship oriented towards the future, support for the relationship to strengthen the actual links.
Édouard Gardella
doaj  

Le droit dans l’urgence. La jurisprudence face aux marginaux (xiiie et xxesiècles)

open access: yesTracés, 2006
Plonger le droit dans l’urgence consiste à rompre avec la vision transcendante de l’activité normative et à immerger le lecteur au moment précis où le droit est encore une activité sociale, et pas encore un ensemble de catégories à appliquer.
Arnaud Fossier, Édouard Gardella
doaj   +1 more source

Second-order Economic Voting in Elections to the European Parliament

open access: yesPapers
When examining citizens’ behaviour in elections to the European Parliament (EP), second order elections (SOE) and economic voting (EV) have overlooked each other as alien traditions.
Agustí Bosch Gardella
doaj   +1 more source

Phalaris. A Journal of Architecture

open access: yesFestival dell'Architettura Magazine, 2018
The invention of a Journal of Architecture appears to us as the story of a great intellectual adventure, which consists of travel insights, art, literature, cinema, theater and architecture.
Luciano Semerani
doaj   +1 more source

CONSEQÜÈNCIES INSTITUCIONALS DE LA LIMITACIÓ DEL DEUTE PÚBLIC A LES COMUNITATS AUTÒNOMES I ALS LÄNDER. UNA ANÀLISI COMPARADA DELS MECANISMES DE CONTROL DE L’ESTABILITAT PRESSUPOSTÀRIA A ESPANYA I ALEMANYA [PDF]

open access: yes, 2014
Aquest article té per objectiu analitzar, des d’una perspectiva del dret comparat, els mecanismes de control establerts per garantir el compliment de la limitació constitucional del deute públic a Espanya i Alemanya.
Darnaculleta Gardella, M. Mercè
core   +1 more source

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