Results 111 to 120 of about 13,854 (246)

Simulated Media for Mimicking the Human Environment In Vitro

APMIS, Volume 133, Issue 4, April 2025.
ABSTRACT The phrase ‘All models are wrong but some are useful’ spoken by George Box in 1976 is as relevant today as ever. Modern research relies heavily on models and the use of in vitro models is the cornerstone of developing novel treatments for various infectious diseases.
Bethan Roberts, Ida Thaarup
wiley   +1 more source

Type II Restriction-Modification System from Gardnerella vaginalis ATCC 14018

Pathogens, 2020
Intensive horizontal gene transfer may generate diversity and heterogeneity within the genus Gardnerella. Restriction-modification (R-M) systems and CRISPR-Cas are the principal defense tools against foreign DNA in bacteria.
Aistė Bulavaitė, Indre Dalgediene, Vilma Michailoviene, Milda Pleckaityte   +3 more
doaj   +1 more source

Distinct cervical tissue-adherent and luminal microbiome communities correlate with mucosal host gene expression and protein levels in Kenyan sex workers

Microbiome, 2023
Background The majority of studies characterizing female genital tract microbiota have focused on luminal organisms, while the presence and impact of tissue-adherent ectocervical microbiota remain incompletely understood.
Gabriella Edfeldt, Vilde Kaldhusdal, Paulo Czarnewski, Frideborg Bradley, Sofia Bergström, Julie Lajoie, Jiawu Xu, Anna Månberg, Joshua Kimani, Julius Oyugi, Peter Nilsson, Annelie Tjernlund, Keith R. Fowke, Douglas S. Kwon, Kristina Broliden   +14 more
doaj   +1 more source

PCR múltiplex para el diagnóstico de microorganismos atípicos transmitidos sexualmente

Perinatología y Reproducción Humana, 2023
Antecedentes: Las infecciones de transmisión sexual son un problema de salud pública mundial. El análisis rutinario incluye solo pruebas microbiológicas y serológicas para el diagnóstico de patógenos.
Marcos R. Escobedo-Guerra, Marcela López-Hurtado, Rodrigo Gutiérrez-Trujillo, Abraham D. Bustos-López, Fernando M. Guerra-Infante   +4 more
doaj   +1 more source

A fruitful alliance: the synergy between Atopobium vaginae and Gardnerella vaginalis in bacterial vaginosis-associated biofilm [PDF]

, 2016
Objectives: Bacterial vaginosis (BV) is characterised by a change in the microbial composition of the vagina. The BV-associated organisms outnumber the health-associated Lactobacillus species and form a polymicrobial biofilm on the vaginal epithelium ...
Abdellati, Said, Crucitti, Tania, De Baetselier, Irith, Hardy, Liselotte, Jespers, Vicky, Musengamana, Viateur, Mwambarangwe, Lambert, van de Wijgert, Janneke, Vaneechoutte, Mario   +8 more
core   +1 more source

ATP13A2 as a prognostic biomarker and its correlation with immune infiltration in cervical cancer: A retrospective study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 7, April 2025.
Abstract While the oncogene ATP13A2 is reportedly involved in colorectal cancer, its role in cervical cancer (CC) has yet to be fully characterized. In this study, we investigated ATP13A2 as a potential prognostic biomarker of CC. To this end, we compared CC tissues with normal tissues to identify differentially expressed genes, identifying ATP13A2 as ...
Zhi Zhao, Yijie Peng, Yuanyuan Yang, Shuaiyu Li, Jiang Ling, Zhenyu Zhu, Chenfeng He   +6 more
wiley   +1 more source

Presence of a polymicrobial endometrial biofilm in patients with bacterial vaginosis. [PDF]

PLoS ONE, 2013
OBJECTIVE: To assess whether the bacterial vaginosis biofilm extends into the upper female genital tract. STUDY DESIGN: Endometrial samples obtained during curettage and fallopian tube samples obtained during salpingectomy were collected. Endometrial and
Alexander Swidsinski, Hans Verstraelen, Vera Loening-Baucke, Sonja Swidsinski, Werner Mendling, Zaher Halwani   +5 more
doaj   +1 more source

Insights into the CRISPR/Cas system of Gardnerella vaginalis [PDF]

BMC Microbiology, 2012
Gardnerella vaginalis is identified as the predominant colonist of the vaginal tracts of women diagnosed with bacterial vaginosis (BV). G. vaginalis can be isolated from healthy women, and an asymptomatic BV state is also recognised. The association of G.
Plečkaitytė, Milda,, Zilnytė, Milda,, Žvirblienė, Aurelija,   +2 more
openaire   +5 more sources

Controversy and multiple roles of the solitary nucleus receptor Nur77 in disease and physiology

The FASEB Journal, Volume 39, Issue 6, 31 March 2025.
Multiple roles of Nur77. Nur77 has complex biological functions, including roles in the nervous system, genome integrity, cell differentiation, cell homeostasis, oxidative stress, autophagy, aging, and infection. Furthermore, Nur77 is implicated in various neurodegenerative diseases and cancers. Abstract Neuron‐derived clone 77 (Nur77), a member of the
Yanteng Wang, Na Li, Wenwei Guan, Difei Wang   +3 more
wiley   +1 more source

Vaginal Prevotella timonensis Bacteria Enhance HIV‐1 Uptake and Differentially Affect Transmission by Distinct Primary Dendritic Cell Subsets

European Journal of Immunology, Volume 55, Issue 3, March 2025.
The bacterium Prevotella timonensis found in vaginal dysbiosis enhances the uptake of HIV‐1 by primary dendritic cells. Virus is internalised into tetraspanin‐rich compartments, which leads to efficient HIV‐1 transmission to target cells. These results provide insight into how microbiota directly affect HIV‐1 uptake thereby altering HIV‐1 ...
Marleen Y. van Smoorenburg, Ester B. M. Remmerswaal, Celia Segui‐Perez, John L. van Hamme, Karin Strijbis, Teunis B. H. Geijtenbeek   +5 more
wiley   +1 more source