Results 31 to 40 of about 22,009 (278)

Glycogen availability and pH variation in a medium simulating vaginal fluid influence the growth of vaginal Lactobacillus species and Gardnerella vaginalis

BMC Microbiology, 2023
Background Glycogen metabolism by Lactobacillus spp. that dominate the healthy vaginal microbiome contributes to a low vaginal pH (3.5–4.5). During bacterial vaginosis (BV), strict and facultative anaerobes including Gardnerella vaginalis become ...
Stephany Navarro, Habib Abla, Betsaida Delgado, J. Colmer-Hamood, G. Ventolini, A. N. Hamood   +5 more
semanticscholar   +1 more source

The Role of the Vaginal Microbiome in Preterm Premature Rupture of Membranes: A Comprehensive Review of Mechanisms and Clinical Implications. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Preterm premature rupture of membranes (PPROM), a complication in approximately 4.5% of pregnancies, is a leading cause of preterm birth and significant perinatal morbidity. A substantial body of evidence implicates vaginal dysbiosis a departure from a healthy, Lactobacillus‐dominant microbiome in the pathogenesis of PPROM.
Alikamali M, Mohammad-Alizadeh-Charandabi S, Ahmadi S, Memar MY, Shahnazi M.   +4 more
europepmc   +2 more sources

Glycogen-Degrading Activities of Catalytic Domains of α-Amylase and α-Amylase-Pullulanase Enzymes Conserved in Gardnerella spp. from the Vaginal Microbiome

bioRxiv, 2023
Increased abundance of Gardnerella spp. is a diagnostic characteristic of bacterial vaginosis, an imbalance in the human vaginal microbiome associated with troubling symptoms, and negative reproductive health outcomes, including increased transmission of
Pashupati Bhandari, Jeffrey P. Tingley, D. W. Abbott, J. Hill   +3 more
semanticscholar   +1 more source

Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses

Microbiome, 2022
The cervicovaginal (CV) microbiome is highly associated with vaginal health and disease in both pregnant and nonpregnant individuals. An overabundance of Gardnerella vaginalis (G.
L. Anton, Briana Ferguson, E. Friedman, K. Gerson, Amy G. Brown, M. Elovitz   +5 more
semanticscholar   +1 more source

Prevotella and Gardnerella Are Associated With Treatment Failure Following First-line Antibiotics for Bacterial Vaginosis

Journal of Infectious Diseases, 2023
Background Bacterial vaginosis (BV) is a common vaginal dysbiosis that often recurs following first-line antibiotics. We investigated if vaginal microbiota composition was associated with BV recurrence. Methods We analyzed samples and data from 121 women
E. Plummer, Amelia M Sfameni, L. Vodstrcil, J. Danielewski, G. Murray, G. Fehler, C. Fairley, S. Garland, E. Chow, J. Hocking, C. Bradshaw   +10 more
semanticscholar   +1 more source

Discrimination of Gardnerella Species by Combining MALDI-TOF Protein Profile, Chaperonin cpn60 Sequences, and Phenotypic Characteristics

Pathogens, 2021
The description of Gardnerella vaginalis was recently updated and three new species, including nine genome species within Gardnerella, were defined using whole genome sequences and matrix assisted laser desorption ionization time of flight (MALDI-TOF ...
Aistė Bulavaitė, Thomas Maier, Milda Pleckaityte   +2 more
doaj   +1 more source

Under conditions closely mimicking vaginal fluid, Lactobacillus jensenii strain 62B produces a bacteriocin-like inhibitory substance that targets and eliminates Gardnerella species

Microbiology, 2023
Within the vaginal ecosystem, lactobacilli and Gardnerella spp. likely interact and influence each other’s growth, yet the details of this interaction are not clearly defined. Using medium simulating vaginal fluid and a two-chamber co-culturing system to
Stephany Navarro, Habib Abla, J. Colmer-Hamood, Gary Ventolini, A. N. Hamood   +4 more
semanticscholar   +1 more source

Cervicovaginal Gardnerella sialidase-encoding gene in persistent human papillomavirus infection

Scientific Reports, 2023
Disturbed vaginal microbiota have a role in the persistence of high-oncogenic-risk human papillomavirus (hrHPV) and Gardnerella spp. is closely related with this condition.
J. Novak, Rafael Belleti, Gabriel Vitor da Silva Pinto, Aline do Nascimento Bolpetti, M. G. da Silva, C. Marconi   +5 more
semanticscholar   +1 more source

Electrospun Fibers with Lactobacillus Acidophilus: A Poten- tial In Vitro Solution Against Gardnerella Infections

Trends in Pharmaceutical Biotechnology, 2023
Bacterial vaginosis (BV) is a prevalent condition, impacting a third of women globally. It’s marked by reduced healthy lactobacilli and increased growth of certain anaerobes like Gardnerella.
Fatima khilonawala, Amjaad Majeed Ali, Mustafa R. AL-Shaheen   +2 more
semanticscholar   +1 more source

Synergistic effects of carvacrol, α-terpinene, γ-terpinene, ρ-cymene and linalool against Gardnerella species

Scientific Reports, 2022
Bacterial vaginosis (BV) is the most common vaginal infection affecting women worldwide. This infection is characterized by the loss of the dominant Lactobacillus community in the vaginal microbiota and an increase of anaerobic bacteria, that leads to ...
Lúcia G V Sousa, J. Castro, C. Cavaleiro, L. Salgueiro, Mariana Tomás, Rita Palmeira-Oliveira, J. Martinez-Oliveira, N. Cerca   +7 more
semanticscholar   +1 more source