Gardnerella vaginalis alters cervicovaginal epithelial cell function through microbe-specific immune responses [PDF]
Microbiome, 2022 Background The cervicovaginal (CV) microbiome is highly associated with vaginal health and disease in both pregnant and nonpregnant individuals. An overabundance of Gardnerella vaginalis (G.
Lauren Anton +5 more
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Frontiers in Cellular and Infection Microbiology, 2020 Koch's postulates dictate the use of experimental models to illustrate features of human disease and provide evidence for a singular organism as the cause.
Nicole M Gilbert, Amanda L Lewis
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Gardnerella vaginalis Enhances Atopobium vaginae Viability in an in vitro Model
Frontiers in Cellular and Infection Microbiology, 2020 Bacterial vaginosis (BV) is the most common vaginal infection among women of reproductive age. A hallmark of BV is the presence of a highly structured polymicrobial biofilm on the vaginal epithelium, presumably initiated by facultative anaerobes of the ...
Joana Castro, Aliona S Rosca, Piet Cools
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Development of the standard mouse model for human bacterial vaginosis induced by Gardnerella vaginalis. [PDF]
Front Vet Sci, 2023 Bacterial vaginosis (BV) is a polymicrobial syndrome characterized by a diminished number of protective bacteria in the vaginal flora. Instead, it is accompanied by a significant increase in facultative and strict anaerobes, including Gardnerella ...
Kwak J +12 more
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Synthetic bacterial consortia transplantation for the treatment of Gardnerella vaginalis-induced bacterial vaginosis in mice. [PDF]
Microbiome, 2023 Bacterial vaginosis (BV) is a disease caused by vaginal microbiota dysbiosis. Here, we propose the use of synthetic bacterial consortia transplantation (SBCT) for the treatment of Gardnerella vaginalis -induced BV mice.
Li Y, Zhu W, Jiang Y, Lessing DJ, Chu W.
europepmc +2 more sources
Transcriptomic and Proteomic Analysis of Gardnerella vaginalis Responding to Acidic pH and Hydrogen Peroxide Stress. [PDF]
Microorganisms, 2023 Gardnerella vaginalis is the main pathogen that causes bacterial vaginosis. In the healthy vaginal microecological environment of a woman, the lactobacilli produce lactate and hydrogen peroxide to inhibit the growth of pathogens such as G. vaginalis. The
Zhang K +7 more
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Glycogen availability and pH variation in a medium simulating vaginal fluid influence the growth of vaginal Lactobacillus species and Gardnerella vaginalis. [PDF]
BMC Microbiol, 2023 Background Glycogen metabolism by Lactobacillus spp. that dominate the healthy vaginal microbiome contributes to a low vaginal pH (3.5–4.5). During bacterial vaginosis (BV), strict and facultative anaerobes including Gardnerella vaginalis become ...
Navarro S +5 more
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Biofilm and pathogenic factor analysis of Gardnerella vaginalis associated with bacterial vaginosis in Northeast China. [PDF]
Front Microbiol, 2022 Introduction Gardnerella vaginalis is a major pathogen responsible for bacterial vaginosis (BV). However, the recurrence of infection and the antibiotic resistance of biofilms remain significant challenges for the treatment of BV. In this study, we aimed
Ma X +5 more
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Prevalence of Gardnerella vaginalis infection and antibiotic resistance pattern of isolates of gynecology clinic patients at Shahriar Noor Hospital from January to June 2020 by PCR and culture methods [PDF]
Iranian Journal of Microbiology, 2023 Background and Objectives: Gardnerella vaginalis is one of the most important causes of prevalent genital infections that pose serious risks. This study aimed to determine the prevalence of Gardnerella vaginalis and antibiotic resistance pattern of ...
Saghi Rashidifar +3 more
doaj +2 more sources
Gardnerella vaginalis clades in pregnancy: New insights into the interactions with the vaginal microbiome. [PDF]
PLoS One, 2022 Gardnerella vaginalis (GV) is an anaerobic bacterial species involved in the pathogenesis of bacterial vaginosis (BV), a condition of vaginal dysbiosis associated with adverse pregnancy outcomes. GV strains are categorized into four clades, characterized
Severgnini M +11 more
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