Results 31 to 40 of about 489,293 (298)

Cosmological Adaptive Mesh Refinement [PDF]

, 1998
We describe a grid-based numerical method for 3D hydrodynamic cosmological simulations which is adaptive in space and time and combines the best features of higher order--accurate Godunov schemes for Eulerian hydrodynamics with adaptive particle--mesh ...
AV Kravtsov, GL Bryan, H Couchman, H Kang, JK Truelove, MJ Berger, MJ Berger, NY Gnedin, P Anninos, P Anninos, P Colella, R Cen, T Abel, U Pen   +13 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

A rapid calculation method for dynamic linepack of natural gas by coupling data and mechanism models

You-qi chuyun
ObjectivePipelines are essential for the long-distance natural gas transportation and play a crucial role in national energy security. The linepack, as a comprehensive operational parameter for natural gas pipeline networks, embodies both safety and ...
Xiong YIN, Jing ZHANG, Fei YANG, Yumo ZHU, Kenan SONG, Jinliang GENG, Kai WEN, Jing GONG   +7 more
doaj   +1 more source

Smoothed-Particle Hydrodynamics Models: Implementation Features on GPUs

, 2017
Parallel implementation features of self-gravitating gas dynamics modeling on multiple GPUs are considered applying the GPU-Direct technology. The parallel algorithm for solving of the self-gravitating gas dynamics problem based on hybrid OpenMP-CUDA ...
Khoperskov, Alexander, Khrapov, Sergey
core   +1 more source

Dynamics of a three-phase upflow fixed bed catalytic reactor [PDF]

, 1999
A dynamic model of an upflow fixed-bed catalytic reactor is developed to examine numerically transient axial temperature and concentration profiles obtained for the consecutive hydrogenation of 1,5,9-cyclododecateriene on a Pd/Al2O3 catalyst.
Delmas, Henri, Julcour-Lebigue, Carine, Le Lann, Jean-Marc, Stüber, Franck, Wilhelm, Anne-Marie   +4 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Gazdynamic characteristics of the centrifugal compressor calculation

Holodilʹnaâ Tehnika i Tehnologiâ, 2018
Gas-dynamic characteristics of the compressor make it possible to evaluate its energy and economic properties, to predict the values of capacity, the generated gas pressure and the power consumption during the compressor operation.
M. Kalinkevych, V. Ihnatenko
doaj   +1 more source

The State of the Circumstellar Medium Surrounding Gamma-Ray Burst Sources and its Effect on the Afterglow Appearance

, 2004
We present a numerical investigation of the contribution of the presupernova ejecta of Wolf-Rayet stars to the environment surrounding gamma-ray bursts (GRBs), and describe how this external matter can affect the observable afterglow characteristics.
Brenda Perez‐Rendon, Chiosi C., Enrico Ramirez‐Ruiz, Garcia-Segura G., Garcia-Segura G., Guillermo Garcia‐Segura, Hartquist T. W., Jay D. Salmonson, Langer N., Langer N., Langer N., McKee C. F.   +11 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source