Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Gazdynamic characteristics of the centrifugal compressor calculation
Gas-dynamic characteristics of the compressor make it possible to evaluate its energy and economic properties, to predict the values of capacity, the generated gas pressure and the power consumption during the compressor operation.
M. Kalinkevych, V. Ihnatenko
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Computer Modelling of Dynamic Processes [PDF]
Results of numerical modeling of dynamic problems are summed in the article up. These problems are characteristic for various areas of human activity, in particular for problem solving in ecology. The following problems are considered in the present work:
B. Rybakin
doaj
Unstady heat-mass-transfer and fuel distributions in flows downstream the gas-dynamic flame holder
A model of non-stationary heat and mass transfer of fuel droplets with a swirling air flow is developed. The model includes the definition of the air flow structure, identification of configurations of liquid jets flowing into the air flow, the ...
V. V. Tretyakov, A. A. Sviridenkov
doaj +1 more source
Characteristics of mass transfer between gas-liquid phases in a higee reactor [PDF]
In the absorption process of gas-liquid phases in Rotating Packed Bed (RPB), the liquid flow on packing was assumed to be film-flow. Based on Higbie’s penetration theory, the diffusion-reaction model in RPB was introduced to calculate the rate ...
Zhenzhen Zhang +4 more
doaj +1 more source
Metal oxide semiconductor (MOS) thin films are of critical importance to both fundamental research and practical applications of gas sensors. Herein, a high-performance H2 sensor based on palladium (Pd) and rhodium (Rh) co-functionalized Fe2 O3 films ...
Lihao Zhou +8 more
semanticscholar +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Design of compressor unit based on wave compressor with magnetoelectric drive for extraction of hydrocarbons in Arctic shelf [PDF]
For the use in such extreme working conditions as underwater offshore production on the Arctic shelf, the use of fundamentally new types of compressor units is required.
S. V. Goryunov +5 more
doaj +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source

