Results 31 to 40 of about 1,205,026 (269)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Medicina Veterinária, 2011 Com a evolução da indústria farmacêutica, muitos medicamentos têm sido lançados e utilizados em pacientes humanos e veterinários, porém, o uso destes podem causar reações adversas, mesmo quando empregados nas doses e intervalos recomendados.
GAS Aleixo
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Proceedings of the Nutrition Society, 1975 Patients with functional bowel disease commonly complain of abdominal pain, bloating, and excessive flatulence and eructation. Pain and bloating may be primarily caused by abnormal intestinal motility rather than by excessive intestinal gas. As yet there are no data available that prove excessive flatulence is actually caused by the presence of ...
openaire +3 more sources
Medicina Veterinária, 2011 O glicosímetro é um equipamento portátil utilizado para mensurar a concentração de glicose no sangue, sendo a maioria dos aparelhos projetados para amostras de sangue capilar. Através desse estudo, objetivou-se avaliar a utilização de sangue venoso para
GAS Aleixo
doaj
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Religious Discourse on Gender Identity: Freedom of Expression or Hate Speech? A European Perspective
ReligionsThis paper explores the complexities arising from the intersection of religious freedom and the principles of gender equality and non-discrimination, a pressing issue within the modern European landscape.
Montserrat Gas-Aixendri
doaj +1 more source
Function and Disability Journal, 2020 Background and Objectives: The color vision evaluation of gas station workers in Isfahan City. Methods: This cross-sectional comparative study was performed on workers at gas stations in Isfahan; all the workers were men.
Jamileh Abolghasemi +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Medicina Veterinária, 2011 O aumento ou a diminuição da taxa de glicose no sangue é uma alteração endócrina comum em seres humanos e animais, e que pode ocasionar graves conseqüências ao estado de saúde dos mesmos.
GAS Aleixo
doaj