Results 141 to 150 of about 3,908,903 (353)

ELABELA Targets Mitochondria to Modulate Heart Development

open access: yesAdvanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang   +22 more
wiley   +1 more source

Розрахунок газових мереж низького тиску з урахуванням зосередженого відбору газу по довжині ділянок [PDF]

open access: yes, 2015
Проведено аналітичні розрахунки, які засвідчили, що нормативні методи прогнозування розподілу газу в системах газопостачання низького тиску з сталевих та поліетиленових труб не достовірно описують наявні газодинамічні процеси.
Ксенич, А. І.
core  

A 3D In Vitro Model of the Human Hepatobiliary Junction

open access: yesAdvanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield   +13 more
wiley   +1 more source

Оцінка матеріального балансу газопроводу в умовах нестаціонарного газоспоживання [PDF]

open access: yes, 2012
За результатами дослідження нестаціонарних процесів коливання тиску в газопроводі, викликаних зміною обсягів споживання газу запропоновано новий метод оцінки кількості газу в газопроводі.Exploring the transient processes in pipeline pressure fluctuations
Дрінь, Н. Я.   +1 more
core  

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

open access: yesAdvanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu   +12 more
wiley   +1 more source

Development and application of pneumatic-electric hybrid magnetic flux leakage detector for gas transmission pipelines

open access: yesYou-qi chuyun
[Objective] This paper focuses on developing a pneumatic-electric hybrid magnetic flux leakage(MFL) detector, examining and verifying its technical advantages to overcome challenges in using traditional air compressor-driven MFL detectors in both newly ...
YIN Cunzhi   +5 more
doaj   +1 more source

Hydrogen Blending into Natural Gas Pipeline Infrastructure: Review of the State of Technology

open access: yes, 2022
Kevin Topolski   +9 more
semanticscholar   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

open access: yesAdvanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang   +14 more
wiley   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

open access: yesAdvanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun   +19 more
wiley   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

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