Results 41 to 50 of about 4,110,038 (308)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

A Numerical Investigation of the Thermal Performance of a Gabion Building Envelope in Cold Regions with a Mountainous Climate

open access: yesApplied Sciences, 2023
Applying rock-filled gabion to buildings in cold regions with mountainous climates has multiple potentials, such as utilizing rock resources, improving building sustainability and saving building energy.
Fang Liu   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Theoretical Study on Impact of Solar Radiation Heat Gain on Thermal Comfort and Energy Efficiency in Glass Curtain Wall Buildings Based on PMV Index

open access: yesBuildings
With rapid global urbanization, glass curtain wall buildings have been widely adopted due to aesthetics and natural lighting. However, during summer time, intense solar radiation leads to significant indoor heat gain, which adversely affect thermal ...
Haoyu Chen   +3 more
doaj   +1 more source

The EU’s Gas Security of Supply: Risk Analysis and Management. EU Diplomacy Paper 10/2011, December 2011 [PDF]

open access: yes, 2011
The energy world is today full of uncertainty: many developments contributed to a situation where it has become increasingly difficult to predict future trends.
Ritter, Anselm
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

The Supply of Gas to the Metropolis [PDF]

open access: yesJournal of the Statistical Society of London, 1876
n ...
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Research and Application of Low-NOx Combustion Technologies for Natural-Gas-Fired Boilers: A Comprehensive Review

open access: yesEnergies
Natural-gas-fired boilers remain widely used for building and industrial heat, making NOx control relevant even as energy systems decarbonize. This comprehensive review synthesizes the published literature on staged combustion, flue-gas recirculation ...
Tao Liu   +6 more
doaj   +1 more source

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