Results 61 to 70 of about 93,505 (269)

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Adsorption and binding dynamics of graphene-supported phospholipid membranes using the QCM-D technique [PDF]

open access: yes, 2018
We report on the adsorption dynamics of phospholipid membranes on graphene-coated substrates using the quartz crystal microbalance with dissipation monitoring (QCM-D) technique.
Goodwin, S.   +5 more
core   +2 more sources

The LacI–Family Transcription Factor, RbsR, Is a Pleiotropic Regulator of Motility, Virulence, Siderophore and Antibiotic Production, Gas Vesicle Morphogenesis and Flotation in Serratia

open access: yesFrontiers in Microbiology, 2017
Gas vesicles (GVs) are proteinaceous, gas-filled organelles used by some bacteria to enable upward movement into favorable air/liquid interfaces in aquatic environments. Serratia sp.
Chin M. Lee   +3 more
doaj   +1 more source

Solid-State NMR Characterization of Gas Vesicle Structure [PDF]

open access: yesBiophysical Journal, 2010
Gas vesicles are gas-filled buoyancy organelles with walls that consist almost exclusively of gas vesicle protein A (GvpA). Intact, collapsed gas vesicles from the cyanobacterium Anabaena flos-aquae were studied by solid-state NMR spectroscopy, and most of the GvpA sequence was assigned.
Sivertsen, Astrid C.   +4 more
openaire   +3 more sources

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon   +10 more
wiley   +1 more source

Using the Photostationary State of Arylazopyrazoles to Control Phase Transitions of Liquid Crystals

open access: yesAdvanced Functional Materials, EarlyView.
A series of new arylazopyrazole photoswitches is designed as dopants for liquid crystalline materials. Unprecedented, the distribution of photoisomers at the photostationary state upon irradiation with light of specific wavelengths (365, 460, 520 nm) is used to control the liquid crystalline phase transitions under isothermal conditions, including ...
Tobias Thiele   +3 more
wiley   +1 more source

CO2-crystal wettability in potassic magmas. Implications for eruptive dynamics in light of experimental evidence for heterogeneous nucleation. [PDF]

open access: yes, 2017
The volatile content in magmas is fundamental for the triggering and style of volcanic eruptions. Carbon dioxide, the second most abundant volatile component in magmas after H2O, is the first to reach saturation upon ascent and depressurization.
Fanara, S.   +4 more
core   +1 more source

Ultrasound Molecular Imaging of Bladder Cancer via Extradomain B Fibronectin-Targeted Biosynthetic GVs

open access: yesInternational Journal of Nanomedicine, 2023
Yanan Feng,1,2,* Yongsheng Hao,3,* Yuanyuan Wang,3 Weijian Song,1,4 Shanxin Zhang,1 Dong Ni,5 Fei Yan,3 Litao Sun1 1Cancer Center, Department of Ultrasound Medicine, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou ...
Feng Y   +7 more
doaj  

Outer membrane vesicles of Dinoroseobacter shibae transport a volatile aldehyde

open access: yesFrontiers in Ecology and Evolution, 2023
Outer Membrane Vesicles (OMVs) of the Gram-negative marine bacterium Dinoroseobacter shibae, a member of the Roseobacteraceae, were investigated for the presence of volatile organic compounds (VOCs).
Diana Koteska   +3 more
doaj   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

open access: yesAdvanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

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