Results 41 to 50 of about 1,306,791 (319)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Carbon Market for Climate Projects in Russia: An Overview of Nature-Based and Technological Carbon Offsets

Gases
Climate projects can become one of the key tools for decarbonization in Russia. They have powerful potential in terms of solving the problems of reducing emissions and increasing the absorption of greenhouse gases, as well as monetization potential for ...
Tatiana Nevzorova
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Experimental Optimization of Natural Gas Injection Timing in a Dual-Fuel Marine Engine to Minimize GHG Emissions

Gases
Phased injection of natural gas into internal combustion marine engines is a promising solution for optimizing performance and reducing harmful emissions, particularly unburned methane, a potent greenhouse gas.
Luigi De Simio, Luca Marchitto, Sabato Iannaccone, Vincenzo Pennino, Nunzio Altieri   +4 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

An Integrated–Intensified Adsorptive-Membrane Reactor Process for Simultaneous Carbon Capture and Hydrogen Production: Multi-Scale Modeling and Simulation

Gases
Minimizing carbon dioxide emissions is crucial due to the generation of energy from fossil fuels. The significance of carbon capture and storage (CCS) technology, which is highly successful in mitigating carbon emissions, has increased. On the other hand,
Seckin Karagoz
doaj   +1 more source

Study of the efficiency of regulation of the process of waterflooding of gas-condensate reservoirs of the Hadiach field using carbon dioxide

Мінеральні ресурси України, 2021
To improve the existing technologies for the development of hydrocarbon reservoirs in the conditions of the manifestation of a water drive, the study of the effectiveness of regulating the flow of formation water into productive reservoirs by injection ...
S. V. Matkivskyi
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Unveiling Radon Concentration in Geothermal Installation: The Role of Indoor Conditions and Human Activity

Gases
The naturally occurring radioactive gas radon presents a major public health danger mainly affecting people who spend time in poorly ventilated buildings.
Dimitrios-Aristotelis Koumpakis, Savvas Petridis, Apostolos Tsakirakis, Ioannis Sourgias, Alexandra V. Michailidou, Christos Vlachokostas   +5 more
doaj   +1 more source

Impact of the well placement density of water flooding process control by injection of carbon dioxide

Мінеральні ресурси України, 2021
Using a 3D-model of a gas condensate field, the influence of the density of the grid of injection wells on the regulation of the process of flooding of the field when injecting carbon dioxide into productive reservoirs on the boundary of the initial gas ...
S. V. Matkivskyi
doaj   +1 more source