Results 151 to 160 of about 139,000 (340)

Population PK and Exposure-Response Analyses of Zolbetuximab in Patients With Locally Advanced Unresectable or Metastatic G/GEJ Adenocarcinoma. [PDF]

open access: yesClin Transl Sci
ABSTRACT Zolbetuximab is a chimeric (mouse/human) monoclonal antibody directed against the tight junction protein claudin 18.2, which is highly expressed in gastric/gastroesophageal junction (G/GEJ) and pancreatic adenocarcinoma. We report a population pharmacokinetic (PK) and exposure‐response (E‐R) analysis of zolbetuximab in patients with locally ...
Yamada A   +5 more
europepmc   +2 more sources

Impact of malnutrition and nutritional support after gastrectomy in patients with gastric cancer

open access: yesAnnals of Gastroenterological Surgery
Malnutrition, characterized by altered body composition and impaired function, is particularly prevalent among gastric cancer patients, affecting up to 60% of them. Malnutrition in these patients can manifest both before and after surgery, due to factors
Min Kyu Kang, Hyuk‐Joon Lee
doaj   +1 more source

Individual's Experience of Living With Roux‐en‐Y Gastric Bypass Surgery: An Interpretative Phenomenological Analysis

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore the lived experience following Roux‐en‐Y gastric bypass surgery of eight men and women in the South of England who had undergone surgery a minimum of 12 months prior. Design This phenomenologically based qualitative study utilised Interpretative Phenomenological Analysis (IPA) as a framework for the analysis and exploration of ...
Nathan Faulkner   +2 more
wiley   +1 more source

Gastric filling ultrasound in assessing gastrointestinal motility in type 2 diabetic patients with neuropathy: A clinical study

open access: yesJournal of Diabetes Investigation, EarlyView.
Gastric filling ultrasound reveals delayed gastric emptying and gastrointestinal dysfunction in patients with type 2 diabetes and neuropathy. These patients exhibit increased gastric filling and decreased small intestine transit rates. Regular assessment of gastrointestinal function is essential to enhance treatment efficacy and quality of life in ...
Juan Yan   +3 more
wiley   +1 more source

Evaluating Malignant Potential of Gastric Adenomas: The Role of Endoscopic Features and Genetic Alterations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim There is no “gold standard” treatment for gastric adenomas due to uncertainty about their malignant potential. We wanted to understand better the factors contributing to their transformation into malignant tumors by analyzing their long‐term development, including endoscopic observations and genetic abnormalities.
Takeshi Ishida   +13 more
wiley   +1 more source

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