Results 81 to 90 of about 139,000 (340)

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

Cancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li, Jianyuan Zhou, Shuang Wang, Qian Yang, Shulun Nie, Chunwang Ji, Xue Zhang, Shuhan Li, Xuanyu Zhou, Jiahui Chu, Xuehui Wu, Jianqiao Jiao, Ruitao Xu, Qian Xu, Miao Huang, Qiushi Wang, Liliang Dou, Qinqin Hu, Fan Jiang, Xin Dai, Zhaodi Nan, Xinyu Song, Di Zhang, Lian Liu   +23 more
wiley   +1 more source

Hospital variation in treatment for synchronous metastatic esophageal and gastric cancer: A nationwide population‐based study in the Netherlands

International Journal of Cancer, EarlyView.
What's New? A range of treatment options exist for metastatic esophageal (EC) and gastric cancer (GC). Which modalities or combination thereof are optimal for these malignancies, however, remains uncertain. Here, the authors examined differences in systemic treatment for metastatic EC and GC across hospitals in the Netherlands.
Julie F. M. Geerts, Pauline A. J. Vissers, Bianca Mostert, Bas P. L. Wijnhoven, Brigitte C. M. Haberkorn, Marie‐Paule G. F. Anten, Camiel Rosman, Geert‐Jan Creemers, Harm Westdorp, Maurice J. C. van der Sangen, Rob H. A. Verhoeven, Grard A. P. Nieuwenhuijzen   +11 more
wiley   +1 more source

Postoperative complications and prognosis after radical gastrectomy for gastric cancer: a systematic review and meta-analysis of observational studies

World Journal of Surgical Oncology, 2019
BackgroundMany observational studies have reported correlations between postoperative complications and prognosis after radical gastrectomy but the results are controversial.
Shiqi Wang, Lei Xu, Quan Wang, Jipeng Li, Bin Bai, Zheng-yan Li, Xiaoyong Wu, Pengfei Yu, Xuzhao Li, Jichao Yin   +9 more
semanticscholar   +1 more source

Non-robotic minimally invasive gastrectomy as an independent risk factor for postoperative intra-abdominal infectious complications: A single-center, retrospective and propensity score-matched analysis

World Journal of Gastroenterology, 2020
BACKGROUND Minimally invasive surgery for gastric cancer (GC) has gained widespread use as a safe curative procedure especially for early GC. AIM To determine risk factors for postoperative complications after minimally invasive gastrectomy for GC ...
S. Shibasaki, K. Suda, M. Nakauchi, Kenichi Nakamura, K. Kikuchi, K. Inaba, I. Uyama   +6 more
semanticscholar   +1 more source

Conversion therapy with sintilimab combined with chemotherapy and apatinib in stage IV gastric cancer

International Journal of Cancer, EarlyView.
What's New? In selected patients with stage IV gastric cancer, radical surgery after conversion therapy may increase survival benefit; however, there is currently no standard protocol for conversion therapy. This prospective, single‐arm, single‐center, phase 2 study evaluated the feasibility of adding immunotherapy to a conversion treatment regimen to ...
Yong Liu, Qiang Xue, Baogui Wang, Xuewei Ding, Rupeng Zhang, Xiaona Wang, Bin Ke, Xuejun Wang, Ning Liu, Jingyu Deng, Hongjie Zhan, Bin Li, Liangliang Wu, Mingzhi Cai, Li Zhang, Wenbai Huang, Peng Jin, Han Liang   +17 more
wiley   +1 more source

Performance of upper gastrointestinal endoscopy in CDH1 germline pathogenic variant carriers: A multicenter study

International Journal of Cancer, EarlyView.
What's New? Hereditary diffuse gastric cancer, characterized histologically by the presence of signet ring cell carcinoma, is a syndrome primarily caused by pathogenic variants in the CDH1 gene. Preventive strategies include risk‐reducing total gastrectomy and endoscopic surveillance.
Joaquín Castillo‐Iturra, Joan Llach, Irina Luzko, Lara Aguilera, Adrià López‐Fernández, Mara Cruellas, Inmaculada Salces, Maite Herraiz, Virginia Piñol, Gemma Llort, Joaquin Cubiella, Pilar Diez Redondo, Carmen Poves, Fernando Martínez, Ana Guerra, Eduardo Albéniz, Sheyla Montori, Javier Laguna, Anabella Cuestas, Elisa Cantú‐Germano, Antoni Castells, Glòria Fernández‐Esparrach, Francesc Balaguer, Leticia Moreira   +23 more
wiley   +1 more source

The Future of Sleeve Gastrectomy [PDF]

European Endocrinology, 2016
The International Diabetes Federation has recently published a position statement on bariatric surgery. Facing a global diabetes crisis, it has added various types of surgery on the gastrointestinal tract as powerful options among the armamentarium to normalise glycaemia, avoid regular medications and decrease costs in severely obese patients ...
openaire   +3 more sources

Single‐cell sequencing reveals the role of IL‐33+ endothelial subsets in promoting early gastric cancer progression

iMeta, EarlyView.
A single‐cell atlas was established to reveal the molecular characteristics of early gastric cancer (EGC). In combination with organoids, animal models, and clinical samples, it was found that subpopulations such as pit mucous‐like cell (PMC‐like), proliferating cell (PC), CH25H+ CD4+ T cell, IL‐33+ endothelial cell, and ADAMTSL2+ endothelial cell are ...
Li Zhou, Mei Yang, Chao Deng, Manqiu Hu, Suhua Wu, Kewen Lai, Lili Zhang, Zhiji Chen, Qin Tang, Qingliang Wang, Lu Chen, Runmin Zha, Yuanyuan Chen, Yibo Tan, Song He, Zhihang Zhou   +15 more
wiley   +1 more source

The impact of the novel EUS scope and ultrasonographic system for diagnosis and therapy in patients with pancreatobiliary diseases (videos)

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Purpose We evaluated the diagnostic and therapeutic capabilities of endoscopic ultrasonography (EUS) in pancreaticobiliary diseases. We aimed to validate the efficiency of detective flow imaging (DFI), shear wave elastography (SWE), and other advanced imaging techniques.
Hiroyuki Kojima, Takao Itoi, Atsushi Sofuni, Takayoshi Tsuchiya, Reina Tanaka, Ryosuke Tonozuka, Shuntaro Mukai, Kenjiro Yamamoto, Yukitoshi Matsunami, Hirohito Minami   +9 more
wiley   +1 more source

Applicability of the Proposed Japanese Model for the Classification of Gastric Cancer Location: The “PROTRADIST” Retrospective Study

Journal of Investigative Surgery, 2017
Background: The extension of lymphadenectomy for surgical treatment of gastric cancer remains discordant among European and Japanese surgeons. Kinami et al. (Kinami S, Fujimura T, Ojima E, et al.
Luigi Marano, Marianna Petrillo, Modestino Pezzella, Alberto Patriti, Bartolomeo Braccio, Giuseppe Esposito, Michele Grassia, Angela Romano, Francesco Torelli, Raffaele De Luca, Alessio Fabozzi, Giuseppe Falco, Natale Di Martino   +12 more
doaj   +1 more source