Results 231 to 240 of about 512,271 (354)

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

Prenatal and Early Childhood Exposure to Antibiotics or Gastric Acid Inhibitors and Increased Risk of Epilepsy: A Nationwide Population-Based Study. [PDF]

Clin Pharmacol Ther
Gudnadottir U, Wickström R, Gunnerbeck A, Prast-Nielsen S, Brusselaers N.   +4 more
europepmc   +1 more source

The H+/K+-ATPase inhibitory activities of Trametenolic acid B from Trametes lactinea (Berk.) Pat, and its effects on gastric cancer cells

, 2013
Qiaoyin Zhang, Nianyu Huang, Junzhi Wang, Huajun Luo, Haibo He, Mingruo Ding, Wei Deng, Kun Zou   +7 more
openalex   +1 more source

Assay of gastrin by means of its gastric acid stimulating activity [PDF]

, 1968
E L Blair, R. M. Keenlyside, D. J. Newell, J D Reed, Diana D. Richardson   +4 more
openalex   +1 more source

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Hesperidin enhances broiler growth performance by augmenting gastric acid secretion via the proton pump pathway. [PDF]

Poult Sci
Li Y, An M, Wan S, Li Y, Du Y, Zhao Y, Li H, Zhong Q, Sun Z.   +8 more
europepmc   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Analyzing Prescribing Trends of Gastric Acid Suppressants in the UK Using Segmented Regression: Evaluating the Influence of COVID-19 (2019-2024). [PDF]

Healthcare (Basel)
Orayj K.
europepmc   +1 more source

Effect of Gastric Acid on Surface Roughness and Color Stability of 3D-Printed Permanent Resins

Gökçen Ateş, Pınar Şeşen
openalex   +2 more sources

Genomic features of the Helicobacter pylori strain PMSS1 and its virulence attributes as deduced from its in vivo colonisation patterns

, 2018
Alikhan, Arnold, Aspholm, Aziz, Backert, Backert, Bankevich, Barrozo, Bartfeld, Bauer, Belogolova, Bonsor, Cao, Censini, Deguchi, Dixon, Draper, Farnbacher, Fischer, Gall, Gaudet, Gomez-Duarte, Gressmann, Higashi, Ishijima, Israel, Jang, Javaheri, Koch, Kusters, Königer, Lai, Lee, Lind, Linz, Lowenthal, Odenbreit, Olbermann, Philpott, Salama, Schmitt, Stein, Talarico, Tammer, Tan, Treangen, Viala, Zimmermann   +47 more
core   +1 more source