Results 351 to 360 of about 5,895,661 (425)
Multi‐Module Micro/Nanorobots for Biomedical and Environmental Remediation Applications
Advanced Intelligent Systems, EarlyView.Multi‐module microrobots (MNRs) have overcome the limitations of single‐module systems by integrating components such as propeller, actuator, manipulator, and imaging modalities. They show promise in biomedical applications, such as targeted drug delivery and tissue repair, as well as in environmental remediation, including pollutant removal.
Bairong Zhu +4 more
wiley +1 more source
Hierarchical Superposition Framework Reveals the Complex Effects of Natural Medicine Formulas
Advanced Intelligent Systems, EarlyView.A novel hierarchical superposition pharmacological model incorporates the principle of hierarchical structures from physics to simulate the spatiotemporal dynamics of drug combinations, to elucidate the universal law underlying drug combination effects. By modeling cross‐level causal transmission and attenuation, it advances beyond traditional additive
Weifeng Liang +3 more
wiley +1 more source
Gut Microbiome Pilot Study of Patients With CHARGE Syndrome and Sibling Controls
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Difficulties with feeding and digestion are common in individuals with CHARGE syndrome. Animal models with CHD7 gene variants demonstrate abnormal gut innovation and dysmotility. Our pilot study evaluated whether individuals with CHARGE syndrome have differences in their gut microbiome compared to unaffected siblings.
Emily R. Chedrawe +5 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The interstitial 6p microdeletion syndrome is characterized by dysmorphic facies and structural heart, kidney, brain, and musculoskeletal differences. RREB1 haploinsufficiency and consequent abnormal RAS‐MAPK pathway signaling have been proposed as a driver of the disease phenotype; however, apart from a single case report, the phenotype of ...
Alanna Strong +16 more
wiley +1 more source
Antiviral effects and mechanism of Qi pi pill against influenza viruses
Animal Models and Experimental Medicine, EarlyView.Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang +10 more
wiley +1 more source
Effect of Exclusion of Bile from the Intestine on Gastric Acid Secretion
, 1967 David L. Nahrwold, Morton I. Grossman
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.The hypothesis diagram illustrates the function and mechanism of circNR3C2: circNR3C2 overexpression can up‐regulate COL2, Aggrecan and SOX9 expression, and regulate chondrogenic differentiation of hADSCs by targeting hsa‐miR‐647. Abstract Background Human adipose‐derived stem cells (hADSCs) are seed cells with application prospects in cartilage repair.
Dabiao Hou +5 more
wiley +1 more source