Results 191 to 200 of about 14,930 (305)

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Challenges of modeling pristane‐induced lupus in non‐human primates

Animal Models and Experimental Medicine, EarlyView.
Systemic lupus erythematosus (SLE) in cynomolgus monkeys was modeled by two intraperitoneal injections of pristane at a dose of 3.5 mL/kg, administered at weeks 1 and 23. Serum samples from all monkeys that received pristane tested positive for antinuclear antibodies.
Elena Vladimirovna Vinogradova, Maria Alexandrovna Varavko, Yakov Yuryevich Ustyugov, Alexey Alexandrovich Aleksandrov, Dmitry Alexandrovich Khochenkov, Yulia Nikolaevna Linkova   +5 more
wiley   +1 more source

A critical role for gastric xanthine oxidoreductase in the formation of S-nitrosothiols and blood pressure responses to nitrite in rats. [PDF]

Redox Biol
de Azevedo Medeiros CF, Neto-Neves EM, Santana IV, Sanches-Lopes JM, Nogueira RC, Batista RIM, Conde-Tella SO, Montenegro MF, Tanus-Santos JE.   +8 more
europepmc   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, EarlyView.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Biopolymer Development from Agro-Food and Aquaculture By-Products with Antioxidant Hydrolysates of <i>Cyprinus carpio</i>, Produced via Enzymatic Preparations of Pineapple and Papaya. [PDF]

Int J Mol Sci
López-García G, Dublán-García O, López-Medina FA, Morachis-Valdez AG, Saucedo-Vence K, Arizmendi-Cotero D, Díaz-Bandera D, Heredia-García G, Santillán-Álvarez A, Cira-Chávez LA, Quintero-Salazar B.   +10 more
europepmc   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Depolymerization and Oxidation Events in Used Frying Oils Under Conditions Simulating Gastric Digestion. [PDF]

Foods
Márquez-Ruiz G, Ruiz-Méndez MV, Holgado F.   +2 more
europepmc   +1 more source

Ag- and Zn-clinoptilolite: a comparison of their in-vitro antibacterial activity against Helicobacter pylori. [PDF]

Environ Geochem Health
Cerri G, Brundu A, Juliano CC, Farina M.
europepmc   +1 more source

Evaluation of probiotic properties of Bacillus aryabhattai HY1 isolated from Vietnamese pickled mustard greens. [PDF]

Sci Rep
Pham MT, Nguyen PTU, Nguyen THY, Ma KL, Chau TD.   +4 more
europepmc   +1 more source