Results 21 to 30 of about 9,492 (194)

Pharmacological effects of aqueous–ethanolic extract of Hibiscus rosasinensis on volume and acidity of stimulated gastric secretion [PDF]

open access: yes, 2011
ObjectiveTo explore the effects of extract of Hibiscus rosasinensis (H. rosasinensis) on the volume, free and total acidity of gastric secretion induced by carbachol.MethodsAnimals were kept on fasting for 48 h, then the pylorus of each animal was ...
Choudhury, Avijit   +3 more
core   +1 more source

Costus afer (Costaceae, Zingiberales) leaf extract ameliorates naproxen-induced gastric ulcer in rats [PDF]

open access: yes, 2021
Purpose: To examine Costus afer leaf extract (CALE) protective effects against naproxen-induced gastric ulcer and the mechanisms of protection.Methods: Rats with naproxen-induced ulcer were pretreated with either CALE (800 mg/kg), pantoprazole (20 mg/kg),
Aljehany, Buthaina M., Khattab, Hala AH
core   +2 more sources

Ameliorative effect of Albizzia procera leaves extract against experimentally induced gastric ulcer models in Wistar albino rats [PDF]

open access: yes, 2021
Albizzia procera belongs to family Fabaceae and has several phytoconstituents like flavonoids, terpenes, alkaloids, saponins etc. The plant is commonly used in traditional medicines.
Goel, Kapil Kumar   +3 more
core   +2 more sources

Wear of human teeth: a tribological perspective [PDF]

open access: yes, 2005
The four main types of wear in teeth are attrition (enamel-on-enamel contact), abrasion (wear due to abrasive particles in food or toothpaste), abfraction (cracking in enamel and subsequent material loss), and erosion (chemical decomposition of the tooth)
Amaechi B. T.   +18 more
core   +2 more sources

Biochemical and spectroscopic properties of Brucella microti glutamate decarboxylase, a key component of the glutamate-dependent acid resistance system [PDF]

open access: yes, 2015
In orally acquired bacteria, the ability to counteract extreme acid stress (pH < 2.5) ensures survival during transit through the animal host stomach. In several neutralophilic bacteria, the glutamate-dependent acid resistance system (GDAR) is the most ...
A. Occhialini   +4 more
core   +3 more sources

The effect of ultrasound pretreatment on some selected physicochemical properties of black cumin (Nigella Sativa) [PDF]

open access: yes, 2018
Background In the present study, the effects of ultrasound pretreatment parameters including irradiation time and power on the quantity of the extracted phenolic compounds quantity as well as on some selected physicochemical properties ...
A Jiménez   +42 more
core   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Antiulcer activity of hydroalcoholic extract of unripe fruit of carica papaya in experimental rats [PDF]

open access: yes, 2017
Background: Carica papaya has previously reported antioxidant, analgesic and anti-inflammatory, antibacterial and anti-histaminic activity. Peptic ulcer disease involves inflammation and oxidative stress, so hydroalcoholic extract of Carica papaya fruits
Kaur, Ramandeep, Sen, Kalyan
core   +2 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

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