Results 21 to 30 of about 5,068 (260)
Omeprazol sódico: caracterização das propriedades físico-químicas e desenvolvimento de comprimidos gastro-resistentes [PDF]
, 2009 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.O omeprazol é o fármaco de primeira escolha para o tratamento de desordens ácido-pépticas.
Murakami, Fábio Seigi
core
Gastroprotective Effects of DAS-77 (a Phytomedicine) in Ulcer Models in Rats [PDF]
, 2013 Purpose: DAS-77 is a phytomedicine that contains the dried bark of Mangifera indica and root of Carica papaya. This study investigated the antiulcer effects of DAS-77 in rats.Methods: DAS-77 was administered orally twice daily for five consecutive days ...
Oduntan, BO +4 more
core +2 more sources
Determination of gastric acidity and pH.
Experimental Biology and Medicine, 1924 The free HC1 of the gastric contents may be easily titrated using brom phenol blue as an indicator. The “total acidity” has no chemical meaning. The pH may be determined by means of the Duboscq colorimeter, using quinaldine redas an indicator. The centrifuged gastric contents are measured and an equal measure of distilled water taken as a standard. The
openaire +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Significance of variation in concentration of chlorides, acid, and pepsin, in the gastric contents, with particular reference to the control of gastric acidity [PDF]
, 1929 The concentration -variations of chlorides, acid and pepsin, in gastric contents, have been studied. One hundred investigations of chlorides and acid alone, and fifteen of pepsin were carried out in both normal and pathological cases. Estimations
Mitchell, Thomas Carlyle
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Evaluation of the efficacy of fresh Saccharum officinarum linn goa (var) stem juice against aspirin-induced ulcers in wistar albino rats. [PDF]
, 2023 A research dissertation submitted to the Directorate of Research and Graduate Training in partial fulfillment of the award of Masters of Science in Pharmacology of Makerere University.Back ground: In Uganda, 12% to 25% of the population is living with ...
Kinalwa, Geofrey
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Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source