Results 181 to 190 of about 1,724,249 (286)

Quercetin Attenuates Cisplatin‐Induced Nephrotoxicity While Enhancing Antitumor Efficacy in Gastric Cancer via Cell Type‐Specific Modulation of the ERK1/2 Pathway

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Quercetin alleviates cisplatin‐induced nephrotoxicity while enhancing antitumor efficacy in gastric cancer. ERK1/2 pathway inhibition mediates cell type‐specific downstream effects of quercetin. Quercetin is a promising adjunct to cisplatin‐based chemotherapy for gastric cancer.
Gen Xia   +4 more
wiley   +1 more source

Characterization of patients with medically unexplained intolerance to enteral feeding treated with home parenteral nutrition: A descriptive cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, Volume 50, Issue 7, Page 1024-1030, October 2026.
Abstract Background and Aims Dutch intestinal failure centers are increasingly confronted with patients started on total parenteral nutrition because of reported intolerance to enteral feeding without meeting clinical criteria for intestinal failure.
J. W. Korzilius   +11 more
wiley   +1 more source

Bowel Obstruction After Gastric Bypass Surgery: A Narrative Review. [PDF]

open access: yesCureus
George AP   +11 more
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao   +5 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

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