Results 291 to 300 of about 247,410 (364)

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Advanced management of postoperative hemorrhage following gastric bypass surgery through super-selective celiac artery coil embolization. [PDF]

Radiol Case Rep
Arain NR, Fatima L, Arain UR, Khan AKN.
europepmc   +1 more source

How Do Trauma‐ and Violence‐Informed Care Approaches Underpin Bariatric Surgery Interventions for Type 2 Diabetes Mellitus Remission? A Scoping Review

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT For individuals living with obesity, bariatric surgery is an effective intervention for type 2 diabetes mellitus (T2DM) remission. Given the established relationships between trauma and obesity, and obesity and T2DM, there is a need to examine bariatric surgical practices from a trauma‐ and violence‐informed care (TVIC) perspective.
Michelle Greenway, Michelle Domjancic, Yixuan (Claire) Liu, Alegria Benzaquen, Megan Racey, Susan M. Jack, Diana Sherifali, Carly Whitmore   +7 more
wiley   +1 more source

Increased Risk of Hypoglycemia Following Roux-en-Y Gastric Bypass Surgery in Patients Without Diabetes: a Propensity Score-Matched Analysis. [PDF]

Obes Surg
Toraih EA, Doma M, Atwal AK, Vlassis B, Abdelmaksoud A, Aiash H, Acharya R.   +6 more
europepmc   +1 more source

Autonomous Implants

Advanced Materials, Volume 37, Issue 45, November 13, 2025.
An ideal implant should mimic native tissues such that it can integrate, sense, heal, and continue to function, i.e., be autonomous. Although early, there are good steps taken in this way, e.g., the development of stimuli‐responsive, self‐powering, self‐actuating, self‐healing, self‐regenerating, and self‐aware implants.
Jagan Mohan Dodda, Marcel F. Kunrath, Ling Zhou Zhao, Mahdi Bodaghi, Armin Yousefi, Nureddin Ashammakhi   +5 more
wiley   +1 more source

Regional brain glucose uptake following gastric bypass surgery during normo- and hypoglycemic clamp: a pilot FDG-PET study. [PDF]

Endocrine
Fanni G, Kvernby S, Radhi S, Mathioudaki A, Sundbom M, Haller S, Roman E, Wikström J, Lubberink M, Eriksson JW.   +9 more
europepmc   +1 more source

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

Advanced Science, Volume 12, Issue 44, November 27, 2025.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source

Nomogram for Predicting Suboptimal Weight Loss at Three Years after Roux-en-Y Gastric Bypass Surgery in Chinese Patients with Obesity and Type 2 Diabetes. [PDF]

Obes Facts
Si Y, Zhang H, Han X, Liu W, Tu Y, Ma X, Yu H, Bao Y.   +7 more
europepmc   +1 more source

Artificial intelligence modelling of tyrosine kinase inhibitors at risk of malabsorption and bioavailability‐enhancing strategies

British Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3130-3140, November 2025.
Aims The study aims to predict and improve the absorption of tyrosine kinase inhibitors (TKIs) in patients with malabsorption issues, particularly those who have undergone bariatric surgery or are using proton‐pump inhibitors. The research involves 2 main components: the development of an artificial intelligence (AI) model to identify TKIs that are ...
Daan W. Huntjens, Olivier J. M. Béquignon, Stefanie D. Krens, Mark Löwenberg, Martine E. D. Chamuleau, Remco J. Molenaar, Anita M. G. Kramers, Marianne A. Kuijvenhoven, Imke H. Bartelink   +8 more
wiley   +1 more source

Harnessing chimeric antigen receptor macrophages against solid tumors

Cancer Communications, Volume 45, Issue 11, Page 1344-1366, November 2025.
Abstract Macrophages are prevalent in multiple tumors and exhibit diverse and potent functional activities. Therapeutic reprogramming of macrophage phenotypes represents a promising strategy for cancer immunotherapy. Engineering chimeric antigen receptors (CARs) to endow macrophages with anti‐tumor capacities demonstrated encouraging efficacy ...
Mengru Wang, Zhen Qin, Xiu‐Wu Bian, Yu Shi   +3 more
wiley   +1 more source