Results 71 to 80 of about 1,724,249 (286)

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source

The clinical effectiveness and cost-effectiveness of bariatric (weight loss) surgery for obesity: a systematic review and economic evaluation [PDF]

, 2009
Objectives: to assess the clinical effectiveness and cost-effectiveness of bariatric surgery for obesity.Data sources: seventeen electronic databases were searched [MEDLINE; EMBASE; PreMedline In-Process & Other Non-Indexed Citations; The Cochrane ...
Colquitt, JL, E Loveman, Clegg, A.J., Colquitt, J.L., Colquitt, J L, Baxter, L, Gospodarevskaya, E., Picot, J, Loveman, E, Loveman, E., Jones, Jeremy, J Jones, Picot, J., Baxter, L., AJ Clegg, L Baxter, Jones, J., Clegg, A J, JL Colquitt, Gospodarevskaya, E, Clegg, AJ, J Picot, E Gospodarevskaya, Jones, J   +23 more
core   +1 more source

Shaping the research agenda of pediatric gastroenterology, hepatology, and nutrition: The proposal from an Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) expert group

JPGN Reports, EarlyView.
Abstract The Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) recognized the need to define research priorities and identify knowledge gaps to guide future investigations in pediatric digestive health. Following international examples, SIGENP aimed to provide a structured framework that aligns scientific innovation with ...
Carlo Agostoni, Daniele Alberti, Renata Auricchio, Maria Elisabetta Baldassarre, Osvaldo Borrelli, Matteo Bramuzzo, Teresa Capriati, Carlo Catassi, Sabrina Cenni, Marco Crocco, Salvatore Cucchiara, Luigi Dall'Oglio, Paola De Angelis, Marco Deganello Saccomani, Fabiola Di Dato, Angelo Di Giorgio, Antonella Diamanti, Valeria Dipasquale, Enrico Felici, Ruggiero Francavilla, Valentina Giorgio, Luigi Greco, Raffaele lorio, Flavio Labriola, Paolo Lionetti, Elena Lionetti, Giuseppe Maggiore, Monica Malamisura, Claudia Mandato, Antonio Marseglia, Emanuele Nicastro, Lorenzo Norsa, Salvatore Oliva, Licia Pensabene, Elena Sofia Pieri, Paolo Quitadamo, Giusy Ranucci, Sara Renzo, Claudio Romano, Silvia Salvatore, Luca Scarallo, Maria Immacolata Spagnuolo, Annamaria Staiano, Caterina Strisciuglio, Renato Tambucci, Riccardo Troncone, Pietro Vajro   +46 more
wiley   +1 more source

Reconstruction of leaking gastric pouch after redo Rouxen-Y gastric bypass – revisionary surgery strategy

, 2016
With the rapid development of the knowledge and techniques in bariatric surgery, as well as extensive expansion of indications for metabolic operations, surgeons have started to realize that the procedures they choose are not always suited to the needs ...
Cheng Zhou, William Braun, Wojciech K. Karcz, Ulrich Wellner, Piotr Małczak   +4 more
core   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Revisional Surgeries of Laparoscopic Sleeve Gastrectomy

Diabetes, Metabolic Syndrome and Obesity, 2021
Siyuan Li,* Siqi Jiao,* Siwei Zhang,* Jiangjiao Zhou Department of General Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, People’s Republic of China*These authors contributed equally to this ...
Li S, Jiao S, Zhang S, Zhou J
doaj  

Comparison Of Laparoscopic Sleeve Gastrectomy And Laparoscopic Roux N Y Gastric Bypass Procedures With Reflux Symptom İndex: A Retrospective Study

Van Tıp Dergisi, 2018
INTRODUCTION: We aimed to evaluate the results of the postoperative reflux of morbid obesity that underwent laparoscopic sleeve gastrectomy (LSG) and laparoscopic roux n y gastric bypass (LRYGB) in our study METHODS: We have reviewed 112 patients who ...
Serdar Yormaz, Hüseyin Yılmaz, Hüsnü Alptekin, İlhan Ece, Bayram Çolak, Fahrettin Acar, Ertugrul Kafalı, Enes Şahin, Mustafa Şahin   +8 more
doaj   +1 more source

Previous bariatric surgery was not associated with an increased risk of reintervention within 2 years after knee arthroplasty: A nationwide register‐based study from Denmark

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Obesity is a major risk factor for knee osteoarthritis (KOA). Bariatric surgery (BAS) effectively induces weight loss, but some of these patients subsequently require knee arthroplasty (KA) despite substantial weight reduction. However, the impact of prior BAS on the risk of reintervention, antibiotic use and mortality following KA ...
Saber Muthanna Aljuboori, Janne Petersen, Robin Christensen, Espen Jimenez‐Solem, Line Lund Kårhus, Søren Overgaard   +5 more
wiley   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source