Results 181 to 190 of about 3,763,730 (308)

Erratum: [Corrigendum] FHOD1 is upregulated in gastric cancer and promotes the proliferation and invasion of gastric cancer cells. [PDF]

Oncol Lett
Jiang C, Yuan B, Hang B, Mao JH, Zou X, Wang P.   +5 more
europepmc   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

Conversion Therapy for Stage IV Gastric Cancer: Report From the Expert Consensus Meeting at KINGCA WEEK 2024

Conversion therapy is a treatment strategy that shifts from palliative systemic therapy to curative surgical treatment for primary and/or metastatic stage IV gastric cancer (GC).
Rha, SY, Wyrwicz, Lucjan, Li, G, Li, Guoxin, Uyama, I, Hoon, Hur, Wyrwicz, L, Yoshikawa, T, Koo, Dong-Hoe, Bencivenga, M, Uyama, Ichiro, Yoshikawa, Takaki, Lee, KW, Bencivenga, Maria, van Hillegersberg, Richard, Lee, IS, Han, HS, Lorenzen, S, Kim, Tae-Han, Kim, TH, An, Jiyeong, Han, Hye-Sook, Rha, Sun Young, Badgwell, Brian, Koo, DH, An, J, van Hillegersberg, R, Kim, IH, Kim, In-Ho, Hoon, H, Lorenzen, Sylvie, Lee, In-Seob, Badgwell, B, Lee, Keun-Wook, Dong-Hoe Koo, Sylvie Lorenzen, Ichiro Uyama, Brian Badgwell, Guoxin Li, Sun Young Rha, In-Seob Lee, Richard van Hillegersberg, Maria Bencivenga, Hye-Sook Han, Jiyeong An, Keun-Wook Lee, Hur Hoon, Lucjan Wyrwicz, Takaki Yoshikawa, Kim, Tae-Han;Uyama, Ichiro;Rha, Sun Young;Bencivenga, Maria;An, Jiyeong;Wyrwicz, Lucjan;Koo, Dong-Hoe;van Hillegersberg, Richard;Lee, Keun-Wook;Li, Guoxin;Yoshikawa, Takaki;Badgwell, Brian;Lorenzen, Sylvie;Kim, In-Ho;Lee, In-Seob;Han, Hye-Sook;Hoon, Hur, Tae-Han Kim, In-Ho Kim   +51 more
core   +1 more source

DDX21 Enhances Radiosensitivity in Head and Neck Squamous Cell Carcinoma by Suppressing MK2‐Mediated DNA Damage Response

Advanced Science, EarlyView.
DDX21 suppresses MK2 activation by directly inhibiting Thr334 phosphorylation in a p38‐independent manner, thereby impairing DNA damage response. Clinically, patients with well‐differentiated tumors exhibiting high DDX21 expression are more likely to benefit from adjuvant radiotherapy, whereas those with low DDX21 levels are predisposed to ...
Tianru Yang, Ting Shen, Yanfang Qiu, Wei Zhang, Ziran Zheng, Jiayi Sun, Yuedi Yao, Mianfeng Yao, Jiang Li   +8 more
wiley   +1 more source

cancer Incidence and Mortality in Ardabil: Report of an Ongoing Population-Based Cancer Registry in Iran, 2004-2006 [PDF]

Background: Ardabil cancer registry is the first population-based cancer registry in Iran that was established in 2000. The first report from this registry revealed that Ardabil has one of the highest rate of gastric cardia cancer and the lowest rate of ...
عقلمندی, سهیلا, ملک زاده, رضا, بابایی, مسعود, سجادی, علیرضا, شکوهی گوگانی, بهروز, صمدی, فاطمه, فلاح, مهدی, دیده ور, رضا, رمضانی, رشید, حکمت, شراره, جعفرزاده, حمید, هایوکا, ج, یزدانبد, عباس   +12 more
core  

Micro- and nanoplastics in gastric cancer: A narrative review. [PDF]

Toxicol Rep
Russel JS, Khute S, Choi J, Park S, Rahman M, Rani A, Kim B, Subash P.   +7 more
europepmc   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

Advanced Science, EarlyView.
MAPA transforms complex multi‐omics data into biologically coherent functional modules by integrating pathway information with molecular interaction networks. Retrieval‐augmented large language models then generate structured, literature‐informed interpretations.
Yifei Ge, Feifan Zhang, Yijiang Liu, Chao Jiang, Peng Gao, Nguan Soon Tan, Sai Zhang, Yuchen Shen, Qianyi Zhou, Xin Zhou, Xiao Wang, Fangqing Zhao, Chuchu Wang, Xiaotao Shen   +13 more
wiley   +1 more source

Multivisceral resection for locally advanced gastric cancer: an italian multicenter observational study.

, 2013
Large experience on the results of resection of Invaded adjacent organs in Clinical T4 Gastric Cancer ...
di Leo A, Rausei S, Doglietto GB, Pacelli F, Roviello F, Rosa F, Scaringi S, Marrelli D, Cipollari C, Marchet A, DE MANZONI, Giovanni, Italian Research Group for Gastric Cancer, Nitti D, Cusumano G, DICOSMO, MARIANTONIETTA, Tonelli F   +15 more
core  

Isocyanate‐Modified Melatplatin(IV) Enhances Antitumor Efficacy via TCF4/COL6A3‐Mediated Extracellular Matrix Remodeling and cGAS‐STING Pathway Activation in Bladder Cancer

Advanced Science, EarlyView.
A series of melatonin‐conjugated platinum(IV) prodrugs was functionalized with isocyanate chains (compounds 5‒12). MP‐12C (compound 11) was identified as the lead candidate, with optimal potency and safety. MP‐12C exhibited greater efficacy than cisplatin by increasing intracellular uptake, reshaping the extracellular matrix, activating the cGAS‐STING ...
Linhui Wang, Xiaomeng Liu, Tao Zhu, Zirun Su, Ruiping Liu, Zhe Li, Kaixuan Du, Kaipeng Jia, Chong Fu, Yuda Lin, Zihan Xue, Zhe Zhang, Chong Shen, Yunkai Qie, Zhouliang Wu, Zhiheng Liu, Kangkang Liu, Jingyuan Xu, Hailong Hu   +18 more
wiley   +1 more source