Results 231 to 240 of about 670,295 (308)

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

Advanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang, Hui Yang, Baoyuan Zhang, Yongsu Ma, Kuangen Zhang, Peng Wang, Jiapeng Yang, Zaiqi Wang, Rong Liu, Xiaodong Tian, Ning Zhang, Yinmo Yang   +11 more
wiley   +1 more source

Correction to "Multigene Germline Panel Testing in Gastric Cancer Patients in a Portuguese Population". [PDF]

Cancer Med
europepmc   +1 more source

Excipient Emulsion–Based Delivery Systems for Enhancing Carotenoid Bioavailability: Advances in Formulation and Gastrointestinal Fate

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Excipient emulsion systems improve carotenoid solubilization, protect against degradation, and enhance gastrointestinal absorption through optimized formulation and digestion behavior. ABSTRACT Carotenoids are bioactive compounds that contribute to human health through antioxidant, provitamin A, and disease‐preventive effects.
Tugce Ceyhan, Elifsu Nemli, Esra Capanoglu, Merve Tomas   +3 more
wiley   +1 more source

p-STAT3 expression associates with prognosis and inflammatory indexes in gastric cancer patients. [PDF]

Sci Rep
Tran DH, Le TS, Nguyen TH, Thai KT, Nguyen TML, Nham TPL, Tran ND, Nguyen TL, Nguyen LT, Bui KC.   +9 more
europepmc   +1 more source

Proposal of Early Drain Exchange After Pancreatoduodenectomy From the View of Reducing Postoperative Pancreatic Fistula

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background To mitigate the progression of postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD), appropriate drain management is required, and exchanging drainage tubes is commonly performed. However, the optimal timing of the first drain exchange has not yet been determined.
Taihei Soma, Mihoko Yamada, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Yoshiyasu Kato, Teiichi Sugiura, Katsuhiko Uesaka   +7 more
wiley   +1 more source

The Changing Landscape of Hereditary Diffuse Gastric Cancer. [PDF]

J Gastric Cancer
Vaessen C, Redpath K, Schulpen E, Guilford P.   +3 more
europepmc   +1 more source

Short Distal Resection Margin Does Not Increase Recurrence Risk After R0 Resection for Rectal Neuroendocrine Tumors: A Single‐Institution Retrospective Study of 208 Patients

Annals of Gastroenterological Surgery, EarlyView.
This study evaluated the impact of distal resection margin (DRM) length on recurrence in 208 patients undergoing surgery for rectal neuroendocrine tumors (NETs). Our findings demonstrate that while oncological safety must unquestionably remain the top priority, a short pathological DRM (< 10 mm) does not increase recurrence risk when R0 resection is ...
Kentaro Sato, Shimpei Matsui, Kaoru Nakano, Yuto Maeda, Tatsuki Noguchi, Takashi Sakamoto, Toshiki Mukai, Tomohiro Yamaguchi, Takashi Akiyoshi   +8 more
wiley   +1 more source

Preoperative gastric cancer immune prognostic score (GCIPS) as a novel biomarker for predicting survival in gastric cancer patients after radical resection: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Hu X, Li J, Zhang S.
europepmc   +1 more source

First Successful Regeneration of a Structurally Native‐Like Colon Using a Bioabsorbable Polymer Sheet

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrated that a bioabsorbable polymer sheet (BAPS) can regenerate approximately half the circumference of the colon with native‐like structure and function in an experimental setting. As the model involved immediate closure after perforation and did not reproduce peritonitis, caution is required when considering clinical applicability ...
Junpei Takashima, Mitsuo Miyazawa, Masayasu Aikawa, Daisuke Fujimoto, Hirotoshi Kobayashi   +4 more
wiley   +1 more source