Results 121 to 130 of about 55,714 (331)

Population pharmacokinetics and dosing of dispersible moxifloxacin formulation in children with rifampicin‐resistant tuberculosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Moxifloxacin is a priority drug for treating rifampicin‐resistant tuberculosis (RR‐TB). We assessed the pharmacokinetics of a child‐friendly, dispersible 100 mg tablet moxifloxacin formulation (dispersed in water) compared to the standard 400 mg non‐dispersible formulation (crushed and suspended in water) in children and evaluated current dosing ...
Megan Palmer   +16 more
wiley   +1 more source

Studies of gastric emptying in man [PDF]

open access: yes, 1980
Measurements of gastric emptying in man have "been made 'by scintigraphic methods "based on a rectilinear scanner or gamma camera. Xn. the initial studies with a scanner. indium-113m DTPA was evaluated as a possible radionuclide marker for a test meal
Heading, Robert Campbell
core  

Intestinal absorption of glucose in mice as determined by positron emission tomography. [PDF]

open access: yes, 2018
KEY POINTS:The goal was to determine the importance of the sodium-glucose cotransporter SGLT1 and the glucose uniporter GLUT2 in intestinal glucose absorption during oral glucose tolerance tests (OGTTs) in mice.
Bindslev   +37 more
core   +1 more source

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia   +4 more
wiley   +1 more source

Modeling the Effect of Sleeve Gastrectomy on Gastric Digestion in the Stomach: Insights from Multiphase Flow Modeling [PDF]

open access: yesarXiv
The geometry and motility of the stomach play a critical role in the digestion of ingested liquid meals. Sleeve gastrectomy, a common type of bariatric surgery used to reduce the size of the stomach, significantly alters the stomach's anatomy and motility, which impacts gastric emptying and digestion.
arxiv  

The survey of the effect of ginger extract on gastric residual volume in mechanically ventilated patients hospitalized in the Intensive Care Units [PDF]

open access: yes, 2013
Background and purpose: Delayed gastric emptying in mechanically ventilated patients is common. According to evidences, Ginger can accelerate gastric emptying.
Ali Vakili, M.   +6 more
core  

Itopride for gastric volume, gastric emptying and drinking capacity in functional dyspepsia [PDF]

open access: yes, 2017
AIM: To study the effect of itopride on gastric accommodation, gastric emptying and drinking capacity in functional dyspepsia (FD). Methods: Randomized controlled trial was conducted to check the effect of itopride on gastric accommodation, gastric ...
Abbas, Aamir   +5 more
core   +2 more sources

Engineering antibodies with cancer‐associated binding sites

open access: yesBMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian   +4 more
wiley   +1 more source

Citrus Flavonoids as Antimicrobials

open access: yesChemistry &Biodiversity, EarlyView.
Citrus flavonoids are powerful and versatile antimicrobials whose mechanism of action often involves disruption of the bacterial membrane, thereby minimizing antimicrobial resistance. This study provides a unified perspective. ABSTRACT Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant ...
Rosaria Ciriminna   +6 more
wiley   +1 more source

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