Results 181 to 190 of about 88,283 (359)

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules   +4 more
wiley   +1 more source

Control of Gastric Emptying by Osmolality of Duodenal Contents in Man

open access: bronze, 1975
J. C. Meeroff   +2 more
openalex   +1 more source

Comparison of Pancreatic Fistula Between Robotic‐Assisted and Open Pancreatoduodenectomy: A Comprehensive Evaluation Using an Alternative Fistula Risk Score

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background Robotic‐assisted pancreatoduodenectomy (RPD) offers ergonomic advantages, yet its effect on pancreatic fistula risk remains unclear. This study evaluated RPD safety using the alternative fistula risk score (aFRS). Methods We retrospectively reviewed the pancreatoduodenectomy database at Seoul National University Hospital (2014–2023),
Charnwit Assawasirisin   +7 more
wiley   +1 more source

Ultrasound-based assessment of impaired gastric emptying in patients with hepatitis B cirrhosis. [PDF]

open access: yesClin Exp Med
Li H   +7 more
europepmc   +1 more source

Prognostic Impact of Unplanned Total Pancreatectomy in Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background This study evaluated the clinical significance of an unplanned total pancreatectomy (TP) by comparing surgical outcomes of planned and unplanned TP for pancreatic ductal adenocarcinoma (PDAC). Methods Forty‐two patients who underwent TP for PDAC between 2009 and 2020 at the Kindai University Hospital were retrospectively analyzed ...
Dongha Lee   +9 more
wiley   +1 more source

A Risk Analysis for Ischemic Necrosis of the Remnant Stomach After Distal Pancreatectomy in Patients With Previous Distal Gastrectomy: A Multicenter Retrospective Survey by the Japanese Society of Pancreatic Surgery

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background/Purpose The remnant stomach after distal gastrectomy (DG) which receives its blood supply mainly from the splenic artery (SPA), is at high risk for gastric ischemia following distal pancreatectomy (DP). We investigated the risk factors for ischemic necrosis of the remnant stomach (INS) during or after DP in DG patients.
Takashi Kishi   +9 more
wiley   +1 more source

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