Results 91 to 100 of about 639,206 (312)

Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended‐Release and Immediate‐Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Acetaminophen (APAP), an over‐the‐counter analgesic and antipyretic, can cause hepatotoxicity when ingested in large overdoses. APAP has multiple formulations including immediate‐release (IR) and extended‐release (ER) preparations. A recently published consensus statement on the management of APAP poisoning indicated that management of APAP‐ER
Kyunghee Yang   +8 more
wiley   +1 more source

LINX®, a novel treatment for patients with refractory asthma complicated by gastroesophageal reflux disease: a case report. [PDF]

open access: yes, 2016
BackgroundGastroesophageal reflux disease is one of the most common comorbidities in patients with asthma. Gastroesophageal reflux disease can be linked to difficult-to-control asthma.
Kenyon, Nicholas J   +6 more
core   +2 more sources

Ethylene glycol intoxication (antifreeze poisoning) in a domestic ferret (Mustela putorius furo)

open access: yesVeterinary Record Case Reports, EarlyView.
ABSTRACT An 8‐year‐old, 1.06 kg, male castrated, domestic ferret (Mustela putorius furo), was presented with an antifreeze (ethylene glycol) poisoning. The relevant medical history shows a T‐cell lymphoma diagnosed 8 months ago and was being treated with prednisolone.
Sören Nieweg   +2 more
wiley   +1 more source

Synchronous gastric and duodenal metastases from head and neck squamous cell carcinoma: a unique presentation of upper gastrointestinal bleeding. [PDF]

open access: yes, 2018
Metastatic disease to the stomach or duodenum is an infrequent diagnosis, and head and neck squamous cell carcinoma (HNSCC) is one of the least common primary malignancies that lead to gastric or duodenal metastases.
Daitch, Zachary   +4 more
core   +1 more source

Effects of competition and predation risk from a life history intraguild predator on individual specialisation

open access: yesJournal of Animal Ecology, EarlyView.
Individual niche specialisation is widespread within animal populations and can have important ecological consequences. Predation and competition are known drivers of individual specialisation, but their combined effects are unstudied. This mesocosm experiment shows that competition and predation from a single antagonist can have variable effects on ...
Marine R. A. Richarson, Travis Ingram
wiley   +1 more source

Xpert MTB/RIF assay did not improve diagnosis of pulmonary tuberculosis among child contacts in Rwanda

open access: yesThe Pan African Medical Journal, 2018
INTRODUCTION: to report on the diagnostic yield using the Xpert MTB/RIF assay on gastric lavage samples from children (15 years) who were household contacts of tuberculosis (TB) cases in Kigali, Rwanda.Methods: a cross-sectional study was conducted among
Francine Mwayuma Birungi   +4 more
doaj   +1 more source

Management of xylazine toxicity, overdose, dependence, and withdrawal: A systematic review

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Xylazine, an alpha‐2‐adrenergic agonist, has been increasingly implicated in substance use and overdose crises. However, little is known about its effects on humans. With the growing public health crisis surrounding xylazine, it has become important to recognize and promptly manage symptoms of xylazine toxicity ...
Philipa Owusu‐Antwi   +4 more
wiley   +1 more source

A Novel Protocol for Gastric Lavage in Patients with Aluminum Phosphide Poisoning: A Double-Blind Study [PDF]

open access: yes
Aluminum phosphide poisoning (ALPP) still has no efficient and approved antidote. Supportive care and hemodynamic monitoring are the only choices of treatment.
فرزانه, اسماعیل   +1 more
core   +1 more source

Periostin as a biomarker of airway inflammation [PDF]

open access: yes, 2016
No abstract ...
Johnstone, Steven, McSharry, Charles
core   +1 more source

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone   +28 more
wiley   +1 more source

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