Results 131 to 140 of about 263,814 (246)

Artificial intelligence in endoscopic prediction of submucosal invasion in gastric neoplasms: systematic review and meta-analysis. [PDF]

Clinics (Sao Paulo)
Long D, Zeng J, Jianting Q.
europepmc   +1 more source

Explainable artificial intelligence incorporated with domain knowledge diagnosing early gastric neoplasms under white light endoscopy. [PDF]

NPJ Digit Med, 2023
Dong Z, Wang J, Li Y, Deng Y, Zhou W, Zeng X, Gong D, Liu J, Pan J, Shang R, Xu Y, Xu M, Zhang L, Zhang M, Tao X, Zhu Y, Du H, Lu Z, Yao L, Wu L, Yu H.   +20 more
europepmc   +1 more source

FTSJ3‐Mediated 2′‐O‐Methylation of HSPA5 mRNA Stabilizes BOP1 via SUMOylation to Drive DRP1‐Dependent Mitochondrial Fission and Fatty Acid Oxidation in Lung Squamous Cell Carcinoma

Advanced Science, EarlyView.
The RNA methyltransferase FTSJ3 drives lung squamous cell carcinoma progression by catalyzing 2′‐O‐methylation of HSPA5 mRNA, which stabilizes BOP1 through SUMOylation and activates DRP1/SREBP1‐mediated mitochondrial fission and fatty acid oxidation. Targeting this axis with liposomal siRNA potently suppresses tumor growth and metastasis ABSTRACT Lung ...
Qin Hu, Jiaheng Lin, Yifei Zhu, Ying Liu, Guoren Zhou   +4 more
wiley   +1 more source

Efficacy and safety of traction-assisted endoscopic submucosal dissection for superficial gastric neoplasms: a meta-analysis of randomized controlled trials. [PDF]

Front Oncol
Zhao ZG, Xu WG, Zhang R, Li XM, Yang C, Wang L, Xie J.   +6 more
europepmc   +1 more source

Endoscopic findings of gastric neoplasms in familial adenomatous polyposis are associated with the phenotypic variations and grades of dysplasia. [PDF]

Medicine (Baltimore), 2022
Kobashi M, Iwamuro M, Kuraoka S, Inoo S, Okanoue S, Satomi T, Hamada K, Abe M, Kono Y, Kanzaki H, Kawano S, Tanaka T, Kawahara Y, Okada H.   +13 more
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

Bridge formation method for endoscopic submucosal dissection of early gastric neoplasms along the lesser curvature at the gastric angle. [PDF]

Endoscopy
Liu J, Yang W, Wang X, Fu C, Wang Z, Tang X.   +5 more
europepmc   +1 more source

Publisher Correction: Explainable artificial intelligence incorporated with domain knowledge diagnosing early gastric neoplasms under white light endoscopy. [PDF]

NPJ Digit Med, 2023
Dong Z, Wang J, Li Y, Deng Y, Zhou W, Zeng X, Gong D, Liu J, Pan J, Shang R, Xu Y, Xu M, Zhang L, Zhang M, Tao X, Zhu Y, Du H, Lu Z, Yao L, Wu L, Yu H.   +20 more
europepmc   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source