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Genetic alterations in gastric precancerous lesions. [PDF]

Genetic counseling (Geneva, Switzerland), 2010
To investigate the occurrence of 17p (p53) loss of heterozygosity (LOH) and increased 4N or aneuploidy in gastric precancerous lesions (GPL), and their association with Helicobacter pylori (H pylori) infection. A total of 78 gastric mucosal biopsy specimens, including 10 normal mucosa and 68 gastric precancerous lesions [chronic atrophic gastritis (CAG,
Karaman, A., Pirim, I., Kabalar, M. Esref, Binici, D. Nasir, Ozturk, C.   +4 more
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Gastric Polyps as Precancerous Lesions

Gastrointestinal Endoscopy Clinics of North America, 1997
Gastric polyps cover a wide range of possible diagnoses. Endoscopically, the nature of the lesions can be diagnosed with a high level of probability. Nevertheless, histopathological diagnosis remains mandatory. The macroscopic appearance of gastric polyps is described together with underlying histopathological diagnoses, which are determinative for ...
J M, Schmitz, M, Stolte
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Helicobacter pylori antibody responses and evolution of precancerous gastric lesions in a Chinese population [PDF]

International Journal of Cancer, 2014
Helicobacter pylori-specific proteins are involved in gastric carcinogenesis. To investigate the seroprevalence of six H. pylori-specific antibodies in patients with different gastric histology, and the impact of seropositivities on the evolution of ...
Markus Gerhard, Kai-Feng Pan, Zhexuan Li   +2 more
exaly   +2 more sources

Evaluation of linear gastric ulcer as a precancerous lesion

Gastroenterologia Japonica, 1975
During the recent 13 years from 1961 to 1973, 21 cases of ulcer-carcinoma satisfying Hauser's pathologic criteria have been found endoscopically, 5 cases (2.6%) of which were mucosal carcinoma accompanying linear ulcer over 30 min in length. In addition, one submucosal carcinoma and 2 cases of sub-early gastric carcinoma, partially invaded into the ...
Y, Kohli, S, Toriie, Y, Hashimoto, K, Kawai   +3 more
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Genetic polymorphisms in mediators of inflammation and gastric precancerous lesions

European Journal of Cancer Prevention, 2008
Chronic inflammation induced by Helicobacter pylori is a key process in gastric carcinogenesis. We hypothesized that genetic polymorphisms in important mediators of H. pylori-induced inflammation may influence the risk of developing various grades of precancerous lesions.
Federico, Canzian, Silvia, Franceschi, Martyn, Plummer, Leen-Jan, van Doorn, Yanhui, Lu, Lydie, Gioia-Patricola, Jorge, Vivas, Gladys, Lopez, Richard K, Severson, Ann G, Schwartz, Nubia, Muñoz, Ikuko, Kato   +11 more
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Serum peptide mapping in gastric precancerous lesion and cancer

Journal of Digestive Diseases, 2014
ObjectiveTo construct and verify a diagnostic model using proteomic analysis of serum samples for identifying gastric precancerous lesions and gastric cancer (GC).MethodsThe serum samples from 25 patients with gastric precancerous lesions (chronic atrophic gastritis with mild to moderate dysplasia), 25 GC patients and 25 healthy controls were analyzed ...
Peng, Li, Dan, Ma, Sheng Tao, Zhu, Xu Dong, Tang, Shu Tian, Zhang   +4 more
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Gastric precancerous lesions: interdisciplinary view at the problem

Modern Gastroenterology, 2018
Своєчасне виявлення та ефективна терапія передракових змін шлункового епітелію — одне зі стратегічних завдань сучасної гастроентерології. Представлено інтегральну думку клініцистів та ендоскопістів щодо передракових змін слизової оболонки шлунка — кишкової метаплазії та дисплазії.
Kharchenko, N. V., Mouzyka, S. V., Zaк, M. Yu.   +2 more
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Precancerous gastric lesions and Helicobacter pylori.

Hepato-gastroenterology, 1997
Previous publications in the literature have reported an association between incidence of Helicobacter pylori (HP) infection and gastric cancer. The role of HP in precancerous gastric lesions or in their evolution towards neoplastic disease is not so clear.We studied 174 patients with atrophic gastritis.Intestinal metaplasia (IM) was detected in 165 ...
E, Masci, E, Viale, M, Freschi, M, Porcellati, A, Tittobello   +4 more
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Deregulation of E-Cadherin in Precancerous Lesions and Gastric Cancer

2009
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Chan, AOO, Wong, BCY
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Precancerous lesions and pathological classification of gastric cancer

European Surgery, 1995
Background Dysplasia is the precancerous lesion of the stomach and is classified according to different criteria. Dysplasias are rarely found alone, most commonly in association with carcinoma. Methods The established classification of gastric carcinoma includes site, histological tumour type, histological grade of differentiation, residual (R) tumour ...
P. Hermanek, Ch. Wittekind
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