Results 11 to 20 of about 782,279 (222)

Immunohistochemical expression of cell‐cycle proteins in gastric precancerous lesions

Journal of Gastroenterology and Hepatology, 2008
AbstractBackground:  The early indicator for the subject predisposed to gastric cancer is abnormal proliferation of gastric epithelial cells, such as atrophic gastritis (AG), intestinal metaplasia (IM), and dysplasia, which have been considered as precancerous lesions of gastric cancer.
Anagnostopoulos, G. K., Stefanou, D., Arkoumani, E., Karagiannis, J., Paraskeva, K., Chalkley, L., Habilomati, E., Tsianos, E., Agnantis, N. J.   +8 more
openaire   +4 more sources

p53 alteration in gastric precancerous lesions. [PDF]

The American journal of pathology, 1994
It has been postulated that chronic atrophic gastritis, intestinal metaplasia, and dysplasia are precancerous stages of stomach tumorigenesis. We investigated the timing of p53 alterations in these events of gastric tumorigenesis. Each of 12 cases of archived tissue containing precancerous and cancerous lesions were selected for the detection of p53 ...
SHIAO YH, RUGGE, MASSIMO, CORREA P, LEHMANN HP, SCHEER WD   +4 more
openaire   +3 more sources

Mir-421 in plasma as a potential diagnostic biomarker for precancerous gastric lesions and early gastric cancer [PDF]

PeerJ, 2019
Objective MicroRNA (miR)-421 plays a key role in cancer progression. It has been reported that circulating miR-421may be a potential tumor marker for the diagnosis of several cancers. However, the role of miR-421 in plasma as a potential biomarker in the
Jianlin Chen, Lihua Wu, Yifan Sun, Qi Yin, Xianhua Chen, Siqun Liang, Qingyan Meng, Haihua Long, Fangying Li, Changjun Luo, Xiaorong Xiao   +10 more
doaj   +3 more sources

Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes [PDF]

Pathologica, 2020
Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently diagnosed malignancy and the third leading cause of cancer related death. Gastric carcinogenesis is a multistep and multifactorial process and is the result of the complex interplay between genetic susceptibility and environmental factors.
Gullo, Irene, Grillo, Federica, Mastracci, Luca, Vanoli, Alessandro, Carneiro, Fatima, Saragoni, Luca, Limarzi, Francesco, Ferro, Jacopo, Parente, Paola, Fassan, Matteo   +9 more
openaire   +6 more sources

Gastric precancerous conditions or lesions and Helicobacter pylori [PDF]

Microbiota in Health and Disease
Gastric cancer is one of the most common malignancies and a leading cause of mortality worldwide, mainly caused by Helicobacter pylori (H. pylori). A PubMed literature search was performed to obtain relevant publications associated with gastric precancerous conditions or lesions and H. pylori, published between April 2023 and March 2024.
Areia, M, Dinis-Ribeiro, M.
openaire   +4 more sources

Management of Gastric Precancerous Lesions and Early Cancer: Practice-Oriented Answers to Clinical Questions. [PDF]

Cancers (Basel)
Background/Objectives: Gastric precancerous conditions and early gastric cancer represent a heterogeneous disease spectrum with variable malignant potential and complex management pathways. Despite well-established international guidelines, discrepancies
Capelli C, Gattuso A, Grosso R, Di Marco M, Frazzoni L.   +4 more
europepmc   +2 more sources

Malignant progression of liver cancer progenitors requires lysine acetyltransferase 7–acetylated and cytoplasm‐translocated G protein GαS

Hepatology, EarlyView., 2022
KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou, Kaiwei Jia, Suyuan Wang, Zhenyang Li, Yunhui Li, Shan Lu, Yingyun Yang, Liyuan Zhang, Mu Wang, Yue Dong, Luxin Zhang, Wannian Zhang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou   +15 more
wiley   +1 more source

Korean Gastric Cancer Association- Led Nationwide Survey on Surgically Treated Gastric Cancers in 2019 [PDF]

, 2021
Purpose: The Korean Gastric Cancer Association (KGCA) has been conducting nationwide surveys on patients with surgically treated gastric cancer, every 5 years, since 1995. This study details the results of the survey conducted in 2019.
권인규
core   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Genetic variation in PSCA and risk of gastric advanced preneoplastic lesions and cancer in relation to Helicobacter pylori infection. [PDF]

PLoS ONE, 2013
SNPs in the Prostate Stem Cell Antigen (PSCA) gene have been found associated with gastric cancer (GC) risk in a genome-wide association study. This association has been replicated in several populations.
Cosmeri Rizzato, Ikuko Kato, Martyn Plummer, Nubia Muñoz, Federico Canzian   +4 more
doaj   +1 more source