Results 101 to 110 of about 688,229 (263)

A Dual‐Mode In Situ EV‐miRNA Profiling Platform for Machine‐Learning‐Assisted Gastric Cancer Liquid Biopsy

open access: yesAdvanced Science, EarlyView.
An in situ dual‐mode platform integrates fusogenic liposomes with localized autocatalytic DNA circuits for plasma‐derived extracellular vesicle microRNA analysis. Following membrane fusion, target miRNAs trigger feedback‐assisted LECHA amplification inside intact vesicles, generating fluorescence and electrochemical outputs. Machine learning integrates
Wenbin Li   +15 more
wiley   +1 more source

经容积黏度试验介导的早期摄食训练对急性脑卒中后留置胃管病人的影响

open access: yesHuli yanjiu, 2019
Objective:To investigate the effect of early stage ingestion exercise mediated by volume-viscosity swallow test(V-VST) on the time of extubation in patients with indwelling gastric tube after acute stroke.MethodsFifty patients with acute stroke admitted ...
张晓梅   +6 more
doaj  

A Preclinical Multifunctional Capsule Robot with Unified Diagnosis and Targeted Thermal Therapy for Gastrointestinal Diseases

open access: yesAdvanced Science, EarlyView.
A proof‐of‐concept multifunctional capsule robot integrates diagnostic imaging, magnetic navigation, wireless power transfer, and targeted thermotherapy for gastrointestinal applications. Magnetically guided positioning and stable wireless power enable localized thermal ablation, achieving controlled heating and high cell mortality in vitro.
Heng Zhang   +7 more
wiley   +1 more source

Youngstown Sheet and Tube Company's Campbell Works

open access: yes, 1910
A view of the west end of Youngstown Sheet and Tube Company's Campbell Works, in East Youngstown (Campbell), Ohio, ca. 1910-1919. Named after James A. Campbell, the Campbell Works quickly became one of the Mahoning Valley's leaders in producing finished
Youngstown Sheet and Tube Company
core  

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

open access: yesAdvanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li   +13 more
wiley   +1 more source

An integrated strategy for reducing anastomotic leakage in patients undergoing McKeown esophagectomy

open access: yesHeliyon
Objective: To describe our experience of reducing anastomotic leakage, a problem that has not been properly solved. Methods: Starting in January 2020, we began implementing our integrated strategy (application of an esophageal diameter-approximated ...
Yan Zhang   +10 more
doaj   +1 more source

Youngstown Sheet and Tube Company's Campbell Works boiler house

open access: yes, 1912
Refined waste gas is routed to the boiler house to be utilized as fuel to heat water for production of steam. After the boilers were installed, the building was constructed around them.
Youngstown Sheet and Tube Company
core  

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota‐Associated Kynurenine Accumulation and Macrophage Remodeling

open access: yesAdvanced Science, EarlyView.
Chronic stress reshapes the gut microbiota and enriches Lactobacillus reuteri, promoting microbiota‐associated kynurenine accumulation through altered tryptophan metabolism. Kynurenine drives immunosuppressive remodeling of tumor‐associated macrophages through TNFR2–C/EBPβ signaling, thereby enhancing gastric cancer dissemination.
Sicheng Zhao   +9 more
wiley   +1 more source

Youngstown Sheet and Tube Company's Campbell Works coal tower

open access: yes, 1920
To produce coke for the steel-making process, coal is subjected to a baking process which eliminates undesired byproducts. At the Youngstown Sheet and Tube Company's Campbell works, coal was stored in a coal tower.
Youngstown Sheet and Tube Company
core  

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

open access: yesAdvanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning   +20 more
wiley   +1 more source

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