Results 201 to 210 of about 906,612 (250)

Cancer cell‐selective ectopic expression of CD20 as an antigen enables rituximab repurposing for solid tumour immunotherapy

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
A recombinant AAV delivered tumour gene therapy. NF‐κB drives tumour‐selective antigen (e.g., CD20) expression. Ectopic CD20 enables rituximab repurposing to solid tumours. ADCC, ADCP, and CDC contribute to the antitumour activity. Abstract Background Despite the clinical success of cancer immunotherapies, their efficacy is often compromised by antigen‐
Ziyan Kong   +6 more
wiley   +1 more source

Dietary partitioning mediates species coexistence in the high seas area of northwest Pacific

open access: yesEcography, Volume 2026, Issue 9, September 2026.
Niche partitioning, manifesting along various axes of the ecological niche, is a fundamental mechanism mediating species coexistence in a system. However, the emergence of many species in marine ecosystems would face considerable constraints in achieving coexistence through spatiotemporal differentiation mechanisms under the framework of niche ...
Na Zang   +6 more
wiley   +1 more source

Clinical evaluation of the i-gel Plus supraglottic airway in Japanese patients: A prospective observational study. [PDF]

open access: yesPLoS One
Nakanishi T   +8 more
europepmc   +1 more source

From the sea to DNA barcode: Optimized preservation method for gelatinous zooplankton integrative taxonomy

open access: yesLimnology and Oceanography: Methods, Volume 24, Issue 9, September 2026.
Abstract Assigning taxonomic identity and thus assessing taxonomic diversity in gelatinous zooplankton is challenging due to their fragility and difficult preservation. Formalin fixation compromises DNA integrity, while flash‐freezing, ethanol, and acetone preservation affect morphological features. In this study, we developed a methodological protocol
Claudia Traboni   +4 more
wiley   +1 more source

Improving Proteolysis‐Targeting Chimera Delivery by Targeting Key Biomarkers in Tumor Endocytosis Pathways

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The image illustrates how PROTACs utilize endocytosis, mediated by cell surface proteins, to overcome bioavailability limitations and enable efficient intracellular delivery. ABSTRACT Proteolysis‐targeting chimeras (PROTACs) are promising therapeutic agents for targeted protein degradation via the ubiquitin‐proteasome system; however, their clinical ...
Huahua Chen   +3 more
wiley   +1 more source

Additions to the Acanthaceae of the Flora of Tropical East Africa: two new species from northern Kenya

open access: yesNordic Journal of Botany, Volume 2026, Issue 9, September 2026.
The new species Barleria kulalensis I.Darbysh. & Q.Luke and Dicliptera huriensis I.Darbysh. & Q.Luke are described and illustrated and their extinction risk is assessed provisionally. The former is based on Barleria sp. G of the Flora of Tropical East Africa (FTEA), with recent field observation and collection of this species from the foothills of ...
Iain Darbyshire, Quentin Luke
wiley   +1 more source

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