Results 111 to 120 of about 495,615 (294)

Plasma Proteome Reflects Tissue Damage and Clinical Manifestations in Patients With Inflammatory Myopathies

open access: yesArthritis &Rheumatology, EarlyView.
Objective Tissue‐specific biomarkers that are reliable and associated with clinical manifestations of idiopathic inflammatory myopathy (IIM) are lacking. The blood circulation in individuals serves as a central conduit, allowing communication between tissues and facilitating clearance and recycling of tissue‐derived proteins.
Yue‐Bei Luo   +23 more
wiley   +1 more source

Sema4A neutralization reduces fibrosis and inflammation in a mouse model of systemic sclerosis and a 3D model of immunity‐driven fibrosis

open access: yesArthritis &Rheumatology, Accepted Article.
Objective We previously showed that Semaphorin4A (Sema4A) is elevated in patients with systemic sclerosis (SSc) and promotes inflammation and fibrosis in vitro. Here, we examined the effect of Sema4A neutralization in vivo and in 3D fibrosis models. Methods Sema4A plasma levels were measured by ELISA in healthy controls (n=31) and patients with SSc (n=
Jaime Marty   +21 more
wiley   +1 more source

Inappropriate prescribing of gastric acid suppressants: A systematic literature review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Inappropriate prescribing of gastric acid suppressants (GASs) may compromise treatment outcomes. This study aimed to examine the prevalence of inappropriate prescribing of GASs in all healthcare settings. Methods This PROSPERO‐registered systematic literature review used PubMed and Embase databases to identify original English‐language studies ...
Dhani Wijaya   +5 more
wiley   +1 more source

The effect of celery (Apium graveolens l) ethanol extract on the prevention of gastric ulcers in rats

open access: yesJurnal Keperawatan
Background: Gastric ulcer is an excoriation area of the stomach caused by the destruction of mucosal defense against the predominant factors. One of the efforts that should be made to reduce the incidence of gastric ulcers is a precautionary measure to ...
Dina Dewi Sartika Lestari Ismail   +3 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Controllable engineered probiotic microspheres for treating ulcerative colitis: A cascade enzyme‐catalyzed strategy to restore intestinal redox homeostasis

open access: yesBMEMat, EarlyView.
A dual strategy integrating genetic engineering and physical encapsulation was proposed to enhance the cell viability and antioxidant properties of probiotics. The cascade antioxidant enzymes released from probiotic microspheres restore intestinal redox homeostasis by eliminating intestinal reactive oxygen species for ulcerative colitis treatment ...
Xiaolong Mao   +9 more
wiley   +1 more source

EFEK PEMBERIAN FLUVOXAMINE TERHADAP PERBAIKAN MUKOSA LAMBUNG MENCIT DENGAN GASTRIC ULCER YANG DIINDUKSI STRES [PDF]

open access: yes, 2017
Gastric ulcer is a localized lesion of gastric mucosa caused by necrotic mucosa, and appears as erosion or ulcer. Gastric ulcer is caused by an imbalance of aggressive factors (gastric acid, pepsin) and protective factors (bicarbonate, NO, mucin ...
MAULIDATUL ISLAMIYAH, 051311133127
core   +1 more source

Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

open access: yesBMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao   +3 more
wiley   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

open access: yesBMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li   +6 more
wiley   +1 more source

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