Results 31 to 40 of about 141,935 (272)

Biodegradable stents for the treatment of bowel strictures in Crohn's disease: technical results and challenges

Endoscopy International Open, 2016
Background and study aims: In patients with Crohn’s disease, the idea of biodegradable stents for treatment of bowel strictures with limited effect of endoscopic balloon dilation is tempting and initial results have been promising.
John Gásdal Karstensen, Katrine Risager Christensen, Jørn Brynskov, Claus Rønholt, Peter Vilmann, Jakob Hendel   +5 more
doaj   +1 more source

Safety and efficacy of directly acting antivirals (sofosbuvir and daclatasvir) in treatment of chronic HCV in HIV-HCV co-infected Egyptian patients

Egyptian Liver Journal, 2021
Background Cure of chronic hepatitis C (HCV) in HIV/HCV co-infected patients is a priority due to their increased risk of complications. Daclatasvir and sofosbuvir treatment regimens with or without ribavirin are considered an important chance for better
Inas E L-Khedr Mohamed, Kadry Mohamed EL-Saeed, Mahmoud Hassan Al-Sadik, Christina Alphonse Anwar   +3 more
doaj   +1 more source

Low-dose azathioprine and allopurinol versus azathioprine monotherapy in patients with ulcerative colitis (AAUC): An investigator-initiated, open, multicenter, parallel-arm, randomised controlled trial

EClinicalMedicine, 2022
Summary: Background: Retrospective studies suggest that for patients with ulcerative colitis (UC) combination therapy with low-dose azathioprine and allopurinol (L-AZA/ALLO) may result in higher remission rates than monotherapy with azathioprine (AZA ...
Marianne Kiszka-Kanowitz, Klaus Theede, Sandra Bohn Thomsen, Jacob Tveiten Bjerrum, Jørn Brynskov, Ida Benedikte Gottschalck, Elena Akimenko, Karen Lisa Hilsted, Anders Neumann, Signe Wildt, Lone Larsen, Jens Kristian Munk, Per Holger Ibsen, Huma Gul Rehana Janjua, Lise Lotte Gluud, Anette Mertz-Nielsen   +15 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Hépatite auto-immune déclenchée après une hépatite aigue grave à Epstein Barr virus

The Pan African Medical Journal, 2020
Les hépatites non alphabétiques (Epstein Barr virus -EBV-, Cytomégalovirus -CMV-, Herpes simplex virus -HSV-, Varicelle zona virus -VZV-...) peuvent être un mode de révélation de plusieurs hépatopathies chroniques sous-jacentes dont l´hépatite auto ...
Khaoula El Montacer, Wafaa Hliwa, Fz El Rhaoussi, Mohammed Tahiri, Fouad Haddad, Ahmed Bellabah, Wafaa Badre   +6 more
doaj   +1 more source

First-time use of a porcine small intestine submucosal plug device to close an acquired tracheo-esophageal fistula

Surgical Case Reports, 2023
Background Acquired tracheo-esophageal fistula (TEF) is a rare, life-threatening pathology, responsible for severe comorbidities. Its management is a real therapeutic challenge and remains controversial.
Laura Dessard, Jacques Deflandre, Justine Deflandre, Vincent Moonen, Nicolas Delhougne, Yves Goffart   +5 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Therapeutic strategy for the patients with coexisting gastroesophageal reflux disease and postprandial distress syndrome of functional dyspepsia

JGH Open, 2020
Background and Aim Gastroesophageal reflux disease (GERD) and functional dyspepsia (FD) frequently overlap. However, no accepted treatment has yet been established for such patients.
Kimio Isshi, Hiroto Furuhashi, Koji Nakada   +2 more
doaj   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Targeted metabolomics reveals plasma short-chain fatty acids are associated with metabolic dysfunction-associated steatotic liver disease

BMC Gastroenterology
Background Alterations in the production of short-chain fatty acids (SCFAs) may reflect disturbances in the gut microbiota and have been linked to metabolic dysfunction-associated steatotic liver disease (MASLD). We assessed plasma SCFAs in patients with
Mira Thing, Mikkel Parsberg Werge, Nina Kimer, Liv Eline Hetland, Elias Badal Rashu, Puria Nabilou, Anders Ellekaer Junker, Elisabeth Douglas Galsgaard, Flemming Bendtsen, Johnny Laupsa-Borge, Adrian McCann, Lise Lotte Gluud   +11 more
doaj   +1 more source