Results 41 to 50 of about 141,935 (272)

Les Cancers Digestifs au Burkina Faso : Aspects Épidémiologiques, Diagnostiques et Thérapeutiques

Health Research in Africa
RESUME Introduction. Au Burkina Faso, les cancers digestifs entraînent une mortalité disproportionnée en raison d'un diagnostic tardif, reflétant un défi majeur de santé publique en Afrique subsaharienne.
Sanné Zitgnimian Souleymane, Abdelhadi Gildas Ouédraogo, Zongo Napon Delphine, Koura Mâli, Ouattara Zanga Damien, Coulibaly Aboubacar, Sawadogo Appolinaire   +6 more
doaj   +1 more source

La maladie à IgG4: à propos de 3 cas

The Pan African Medical Journal, 2020
La maladie à IgG4 encore appelée polyexocrinopathie auto-immune à IgG4 est une nouvelle entité où s´inscrit la PAI de type 1. Elle peut toucher différents organes (système nerveux central, les glandes salivaires, la thyroïde, les poumons, le pancréas ...
Hakima Abid, Moulaye El Hacen Horma Babana El Alaoui, Moulay Youssef Alaoui Lamrani, Mouna Figuigui, Beiba Cheikh Ahmed, Nada Lahmidani, Mounia El Yousfi, Dafr-Allah Benajah, Mustapha Maarouf, Mohammed El Abkari, Sidi Adil Ibrahimi, Nourdin Aqodad   +11 more
doaj   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

Advanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin, Xiong Sun, Chengguo Li, Ming Yang, Ke Wu, Ke Liu, Anshu Li, Xiaoming Shuai, Kailin Cai, Zheng Wang, Guobin Wang, Peng Zhang, Jianfeng Shen, Kaixiong Tao, Yuping Yin   +14 more
wiley   +1 more source

La baisse de la densité osseuse au cours des maladies inflammatoires chroniques de l'intestin: prévalence et facteurs de risque

The Pan African Medical Journal, 2013
INTRODUCTION: La baisse de la densité minérale osseuse représente la principale manifestation osseuse décrite au cours des maladies inflammatoires chroniques de l'intestin.
Aida Ben Slama Trabelsi, Faouzi Abdellaoui, Mehdi Ksiaa, Ahlem Souguir, Hela Zeglaoui, Mohamed Ben Rejeb, Ahlem Brahem, Salem Ajmi, Ali Jmaa   +8 more
doaj   +1 more source

Translation of a physiologically‐based pharmacokinetic model for dabigatran etexilate to the design of a safety and efficacy study in post‐partum women

British Journal of Clinical Pharmacology, EarlyView.
Aims To translate a PBPK model developed for the direct oral anticoagulant, dabigatran etexilate, the prodrug of dabigatran, based on data obtained from healthy men to healthy non‐pregnant, pregnant and post‐partum women. To evaluate safety and efficacy of dabigatran etexilate in post‐partum women using simulations and design a future clinical study to
Kayode Ogungbenro, Lorna Aucott, Farhad Kamali, Paul Ayuk   +3 more
wiley   +1 more source

Oesophageal Schwannoma: A Postoperative Diagnosis [PDF]

Journal of Clinical and Diagnostic Research, 2019
Oesophageal schwannomas are rare benign tumours with very few case reports in the literature. It is very difficult to diagnose these tumours preoperatively and is often confused with other benign tumours like leiomyomas and GIST.
Aditya Sharma, Hirdaya Hulas Nag, Phani Kumar Nekarakanti, Vidya Sharada Bhat, Monika Sharma   +4 more
doaj   +1 more source

Therapy of Chronic Viral Hepatitis: The Light at the End of the Tunnel?

Biomedicines, 2022
Chronic viral hepatitis determines significant morbidity and mortality globally and is caused by three main etiological actors (Hepatitis B Virus, Hepatitis C Virus, and Hepatitis D Virus) with different replicative cycles and biological behaviors. Thus,
Giorgio Maria Saracco, Alfredo Marzano, Mario Rizzetto   +2 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Metformin and Hepatocellular Carcinoma Risk Reduction in Diabetic Patients with Chronic Hepatitis C: Fact or Fiction?

Viruses, 2023
Background: Patients with chronic hepatitis C (CHC) and concomitant type 2 diabetes mellitus (DM) show a higher risk of developing hepatocellular carcinoma (HCC).
Marco Sacco, Davide Giuseppe Ribaldone, Giorgio Maria Saracco   +2 more
doaj   +1 more source

Novel Bioactive Multifunctional Polyphenols: A Chemo‐Enzymatic Approach

Chemistry – A European Journal, EarlyView.
One‐step synthesis of complex alkyl oxystilbenin glucosides (6‐47% yield) in alcoholic medium. Switching to ter‐BuOH as solvent afforded δ‐Viniferin diglucoside, with high selectivity and high yield (> 90%), that can be upgraded by enzymatic esterification to alkyl δ‐Viniferin diglucosides.
Amandine L. Flourat, Emilie Thiébault, Agathe Martinez, Fanny Brunissen, Abdouramane Dosso, Floriane Oszust, Sébastien Blaise, Béatrice Romier, Florent Allais   +8 more
wiley   +1 more source