Neuropharmacological effects of Gastrodia elata Blume and its active ingredients [PDF]
Frontiers in NeurologyGastrodia elata Blume (GE), a traditional Chinese medicine clinically employed to treat neurological disorders, demonstrates therapeutic efficacy supported by robust clinical evidence.
Dong Wang +4 more
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Identification and Investigation of miRNAs From Gastrodia elata Blume and Their Potential Function [PDF]
Frontiers in Pharmacology, 2020 Gastrodia elata Blume (G. elata) is a valuable traditional Chinese medicine with neuroprotection, anti-inflammatory, and immune regulatory functions. MicroRNAs (miRNA) is a kind of endogenous noncoding small RNAs that plays distinctly important roles for
Chunxin Xia +10 more
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Neuropharmacological Potential of Gastrodia elata Blume and Its Components. [PDF]
Evid Based Complement Alternat Med, 2015 Research has been conducted in various fields in an attempt to develop new therapeutic agents for incurable neurodegenerative diseases. Gastrodia elata Blume (GE), a traditional herbal medicine, has been used in neurological disorders as an ...
Jang JH +7 more
europepmc +12 more sources
Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities [PDF]
Molecules, 2019 Gastrodia elata Blume (G. elata) is a valuable Traditional Chinese Medicine (TCM) with a wide range of clinical applications. G. elata polysaccharides, as one of the main active ingredients of G.
Haodong Zhu +7 more
doaj +6 more sources
Fresh Gastrodia elata Blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-related pathways [PDF]
Frontiers in Pharmacology, 2023 In aerospace medicine, the influence of microgravity on cognition has always been a risk factor threatening astronauts’ health. The traditional medicinal plant and food material Gastrodia elata Blume has been used as a therapeutic drug for neurological ...
Yiwen Zhang +10 more
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Integrated transcriptome and metabolome provide insight into phenolics and soluble sugar variation in the different varieties of Gastrodia elata Blume from different areas in China [PDF]
Frontiers in Plant ScienceGastrodia elata Blume is known for its "medicinal food homology", its chemical components include phenols, glycosides and polysaccharides. In China, the Anhui, Hubei, Guizhou, and Yunnan provinces are the primary G.
Haixia Wang +17 more
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Glial Nrf2 signaling mediates the neuroprotection exerted by <i>Gastrodia elata</i> Blume in Lrrk2-G2019S Parkinson's disease. [PDF]
Elife, 2021 The most frequent missense mutations in familial Parkinson's disease (PD) occur in the highly conserved LRRK2/PARK8 gene with G2019S mutation. We previously established a fly model of PD carrying the LRRK2-G2019S mutation that exhibited the parkinsonism ...
Lin YE +7 more
europepmc +6 more sources
Research progress of Gastrodia elata Blume polysaccharides: a review of chemical structures and biological activities [PDF]
Frontiers in ChemistryGastrodia elata Blume (G. elata), listed as one of the 34 precious Chinese medicines, servers a dual purpose as both a medicinal herb and a food source. Polysaccharide is the main active ingredient in G.
Liu Yang +4 more
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Genome sequencing and resequencing identified three horizontal gene transfers and uncovered the genetic mechanism on the intraspecies adaptive evolution of Gastrodia elata Blume [PDF]
Frontiers in Plant Science, 2023 Horizontal gene transfer is a rare and useful genetic mechanism in higher plants. Gastrodia elata Blume (GE) (Orchidaceae), well known as traditional medicinal material in East Asia, adopts a heterotrophic lifestyle, thus being considered to be more ...
Yunsheng Wang +3 more
doaj +4 more sources
Gastrodia elata Blume extract suppresses lipid accumulation in high-fat diet-fed rats: a biochemical and histopathological evaluation [PDF]
Laboratory Animal ResearchBackground Excessive consumption of high-fat diet (HFD) can easily cause obesity, hyperlipidemia, and fatty liver disease. Persistent elevation of blood lipid levels increases the risk of cardiovascular disease, with hyperlipidemia being a well ...
Hyeon Jeong Na +6 more
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