Results 91 to 100 of about 1,590 (202)

Anti‐hypertensive effect and potential mechanism of gastrodia‐uncaria granules based on network pharmacology and experimental validation

open access: yesThe Journal of Clinical Hypertension, Volume 26, Issue 9, Page 1024-1038, September 2024.
Abstract Hypertension has become a major contributor to the morbidity and mortality of cardiovascular diseases worldwide. Despite the evidence of the anti‐hypertensive effect of gastrodia‐uncaria granules (GUG) in hypertensive patients, little is known about its potential therapeutic targets as well as the underlying mechanism.
Chu‐Hao Liu   +4 more
wiley   +1 more source

Antidiabetic Molecular Mechanisms of Active Compounds from Several Orchids [PDF]

open access: yes, 2023
Hyperglycemia condition that leads to diabetes causes various complications. Various active compounds from plants have been studied for their antidiabetic abilities. One of them is the orchid plant.
Huang, Tzou-Chi   +3 more
core   +1 more source

Protective Effect of Compound Tongluo Decoction on Brain Vascular Endothelial Cells after Ischemia‐Reperfusion by Inhibition of Ferroptosis Through Regulating Nrf2/ARE/SLC7A11 Signaling Pathway

open access: yesAdvanced Biology, Volume 8, Issue 3, March 2024.
Compound Tongluo Decoction (CTLD) ameliorated IR injury in tMCAO mice. CTLD relieves IR injury via inhibiting ferroptosis in brain cells. CTLD regulated the Nrf2/ARE/SLC7A11 signaling pathway and is verified in Nrf2 ‐/‐ mice. Abstract Cerebral infarction is one of the most common diseases for aged people.
Peiyi Li   +8 more
wiley   +1 more source

Parishin C Attenuates Phencyclidine-Induced Schizophrenia-Like Psychosis in Mice: Involvements of 5-HT1A Receptor

open access: yesJournal of Pharmacological Sciences, 2010
Parishin C, a major component of Gastrodia elata BLUME (GE), was purified from GE. Because GE modulates the serotonergic system and the 5-HT1A receptor is an important therapeutic target of schizophrenia, we examined whether parishin C affects ...
Eun-Joo Shin   +10 more
doaj   +1 more source

Gastrodia elata Blume protects against stress-induced gastric mucosal lesions in mice

open access: yesInternational Journal of Molecular Medicine, 2007
Gastrodia elata Blume (GEB) is a traditional herbal plant that has been used in Asian countries for centuries as an anticonvulsant, analgesic, and also as a sedative for treating general paralysis, epilepsy, vertigo, and tetanus. Although numerous reports have addressed the effects of GEB against degenerative diseases, no previous study has examined ...
Sang-Mi, An   +10 more
openaire   +3 more sources

Gastrodia Elata Bl Attenuates Methamphetamine-Induced Dopaminergic Toxicity Via Inhibiting Oxidative Burdens [PDF]

open access: yes
It has been recognized that Gastrodia elata Bl (GE), an oriental herb medicine, ameliorates various neurological disorders, that GE modulates the monoaminergic and GABAergic systems, and that GE possess antioxidant activities.
Ali, S. F   +10 more
core   +2 more sources

Comparison of anti-oxidant activities of seventy herbs that have been used in Korean traditional medicine [PDF]

open access: yes, 2008
Many herbs have been used as therapeutics in Korean traditional medicine. In view of their clinical indications, anti-oxidant activity may contribute to their pharmacological effects.
1Lee   +32 more
core   +2 more sources

Four new phenolic constituents from the rhizomes of Gastrodia elata Blume

open access: yesNatural Product Research, 2018
Four new gastrodin derivatives containing a trans-cinnamoyl unit (1–4) and nine known compounds (5–13) were isolated from the rhizomes of Gastrodia elata Blume. All these compounds were evaluated for their neuroprotective effects against 6-hydroxydopamine-induced cell death, and compounds 7 and 12 showed potent activities with EC50 values of 10.5 and ...
Zhi-Wei, Wang   +7 more
openaire   +2 more sources

4,4′-methylenediphenol reduces Aβ-induced toxicity in a Caenorhabditis elegans model of Alzheimer’s disease

open access: yesFrontiers in Aging Neuroscience
IntroductionGastrodia elata Blume is a widely used medicinal and edible herb with a rich chemical composition. Moreover, prescriptions containing Gastrodia elata are commonly used for the prevention and treatment of cardiovascular, cerebrovascular, and ...
Xingzhi Yu   +3 more
doaj   +1 more source

The botanical knowledge in urban areas: cognitive enhancers marketed in the metropolitan area of Buenos Aires, Argentina [PDF]

open access: yes, 2020
Este trabajo presenta resultados parciales de una línea de investigación en Etnobotánica urbana, desarrollada por el Laboratorio de Etnobotánica y Botánica Aplicada (LEBA) en el Área Metropolitana de Buenos Aires, Argentina.
Arenas, Patricia Marta   +2 more
core   +2 more sources

Home - About - Disclaimer - Privacy