Results 101 to 110 of about 87,420 (220)

Semaglutide Injection Once‐Weekly for Weight Management in Adults: Results From A Randomized Phase III, Active‐Controlled Study

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8602-8612, September 2026.
ABSTRACT Aim To evaluate and compare the efficacy, safety, and immunogenicity of a synthetic semaglutide injection (Test semaglutide) with Wegovy (Reference semaglutide) injection for weight management. Materials and Methods This randomized, Phase III, non‐inferiority study included adults with obesity or overweight with or without comorbidities from ...
Unnikrishnan Ambika Gopalakrishnan   +26 more
wiley   +1 more source

Treatment With Ruxolitinib and TAK‐779 Enhances GII.17 Human Norovirus Replication and Enables Serial Passaging in Human Intestinal Enteroids

open access: yesGenes to Cells, Volume 31, Issue 5, September 2026.
We aimed to establish a simple method for GII.17 human norovirus (HuNoV) replication and serial passaging using wild‐type J2 human intestinal enteroids (HIEs). Treatment with ruxolitinib and TAK‐779, which target interferon and chemokine signaling, respectively, enhances viral replication and enables serial passaging of GII.17. ABSTRACT Human norovirus
Eri Hiraishi   +4 more
wiley   +1 more source

A Case Series of Sudden Death in Children Aged 12 Months to 4 Years From LPIN1 Deficiency and PPA2 Deficiency in Queensland

open access: yes
Journal of Paediatrics and Child Health, EarlyView.
Sophie Manoy   +11 more
wiley   +1 more source

Imaging Characteristics of Pylorogastric, Duodenogastric, and True‐Gastrogastric Intussusception in 25 Dogs and One Cat

open access: yesVeterinary Radiology &Ultrasound, Volume 67, Issue 5, September 2026.
ABSTRACT Gastric intussusception in dogs and cats is uncommon, and there are multiple variations described in the literature. The aim of this study was to describe the imaging characteristics of pylorogastric (PG), duodenogastric (DG), and true‐gastrogastric (true‐GG) intussusceptions.
Dylan Burton   +9 more
wiley   +1 more source

Expanding the Phenotype of TUFM ‐Related Combined Oxidative Phosphorylation Deficiency 4

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1884-1889, August 2026.
ABSTRACT Combined oxidative phosphorylation deficiency 4 (COXPD4) is a rare mitochondrial condition caused by biallelic deleterious variants in the nuclear‐encoded gene TUFM. To date, most individuals with COXPD4 have presented with encephalopathy, hypotonia, and abnormal brain imaging. Many of the reported individuals died in infancy. We aim to expand
Noémie Villeneuve‐Cloutier   +2 more
wiley   +1 more source

Increasing the reporting of adverse drug reaction‐related hospitalizations using an ICD‐10‐based identification workflow: A multicentre study from Switzerland

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2937-2948, August 2026.
Background Reporting adverse drug reactions (ADRs) is essential for drug safety. In Switzerland, healthcare professionals are legally required to report serious and unlabelled ADRs, yet under‐reporting remains widespread. We tested a novel method to increase reporting of ADR‐related hospitalizations.
Georgia Anita Weber   +7 more
wiley   +1 more source

Multifaceted Roles of Chloroquines in Gastrointestinal Disorders and Beyond

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Chloroquine (CQ) and hydroxychloroquine (HCQ) modulate lysosomal activity and autophagy, suppressing gastrointestinal inflammation and reshaping pathogenic microbiota. These mechanisms alleviate inflammatory bowel disease, inhibit associated tumor growth, and provide benefits in certain autoimmune and viral conditions.
Sihyun Jeong   +3 more
wiley   +1 more source

Rotavirus gastroenteritis among children under five years of age in Izmir, Turkey

open access: yesThe Turkish Journal of Pediatrics, 2003
Little is known about the epidemiology of rotavirus infection in Turkey. The aim of the study was to determine the incidence and clinical significance of rotavirus gastroenteritis, in view of the potentially available prevention by rotavirus ...
Zafer Kurugöl   +9 more
doaj  

Eosinophilic gastroenteritis in a 14-year-old patient with Noonan syndrome with a PTPN11 variation: a case report

open access: yesJournal of Medical Case Reports
Background Noonan syndrome has a wide range of symptoms due to dysregulation of the RAS/MAPK pathway with several gene variations, including the PTPN11 gene. There are currently no case reports of Noonan syndrome with eosinophilic gastroenteritis. Case A
Nobuhiko Koga   +5 more
doaj   +1 more source

Gastrointestinal comorbidities in patients with acne vulgaris: A population-based retrospective studyCapsule Summary

open access: yesJAAD International
Background: The gut-skin-brain axis has been long postulated in acne vulgaris. Few studies focused on bowel habits in patients with acne vulgaris have yielded controversial results.
Yu-Wen Chen, MD   +2 more
doaj   +1 more source

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