Results 141 to 150 of about 125,227 (261)

Managing peptic ulcer and gastroesophageal reflux disease in elderly Chinese patients – focus on esomeprazole

open access: yes, 2013
Raymond SY Tang, Justin CY Wu Institute of Digestive Disease, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Abstract: Peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD) are not ...
Wu JC, Tang RS
core  

Detection of refractory gastroesophageal reflux disease using the method of daily pH-impedance monitoring: a clinical case

open access: yes
Daily pH-impedance monitoring is an effective method for detecting pathologic gastroesophageal refluxes. We would also like to note the value of this method for the diagnosis of refractory gastroesophageal reflux disease (GERD) in the absence of a ...
Natalya N. Dekhnich   +1 more
core   +1 more source

Pathways of Epithelial Barrier Breakdown and Remodeling in Esophageal Organoids by Commonly Used Surfactants

open access: yesAllergy, EarlyView.
This study shows that SDS and CAPB directly impair esophageal epithelial barrier integrity in primary EoE‐derived models. SDS induces stronger inflammatory, oxidative stress, and keratinization responses than CAPB. Both surfactants promote epithelial remodeling and partial epithelial‐mesenchymal transition (EMT), with CAPB showing a distinct ...
Ozge Ardicli   +60 more
wiley   +1 more source

Gastroesophageal reflux disease in COPD: links and risks

open access: yes, 2015
Annemarie L Lee,1–3 Roger S Goldstein1,2,4 1West Park Healthcare Centre, 2Department of Physical Therapy, University of Toronto, Toronto, ON, Canada; 3Institute for Breathing and Sleep, Austin Hospital, Melbourne, VIC, Australia; 4Department of ...
Lee AL, Goldstein RS
core  

Single‐Cell Profiling Links T‐Cell Accumulation and TH2/TH17 Dynamics to Eosinophilic Esophagitis (EoE) Activity in Children

open access: yesAllergy, EarlyView.
Active EoE is associated with more and deeper epithelial eosinophil, mast cell, and T cell infiltration; inactive EoE resembles controls. During remission, PPI treatment leaves more tissue resident CD3+ T‐cells than TS. In active EoE, TH2 cells, IL‐10hi Tregs, and CD8+ cytotoxic T cells are enriched, while TH17 cells are relatively depleted.
Hannes Hoelz   +18 more
wiley   +1 more source

The Evolution in Understanding the Physiological Causes of Dyspnoea in Large Hiatal Herniation: A Narrative Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background The symptomatology of large hiatus hernia (LHH) has been historically poorly understood, with cardiorespiratory symptoms caused by LHH being underappreciated by clinicians. This study reports on the mechanisms of dyspnoea in LHH through a historical review of symptoms and evolved physiological literature, discussing likely causation.
Arunan Mahendravarman   +2 more
wiley   +1 more source

Management of gastroesophageal reflux disease in adults: a pharmacist’s perspective

open access: yes, 2018
Brett MacFarlane1,2 1Australian College of Pharmacy, Canberra, ACT, Australia; 2Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia Abstract: Gastroesophageal reflux disease (GERD) is a common gastrointestinal diagnosis, a ...
MacFarlane B
core  

Efficacy and safety of non-pharmacological interventions for gastroesophageal reflux and gastroesophageal reflux disease in children: a systematic review. [PDF]

open access: yesItal J Pediatr
Banderali G   +15 more
europepmc   +1 more source

Risk Factors for Complications Following Paediatric Neuromuscular and Syndromic Scoliosis Correction Surgery: A Systematic Review

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background Paediatric neuromuscular and syndromic scoliosis patients have multiple medical comorbidities that increase the risk of postoperative complications. There is a lack of consistent literature assessing the specific risk factors for complications following scoliosis correction surgery in this high‐risk cohort.
Mai Pham   +4 more
wiley   +1 more source

Roux‐en‐Y Reconstruction After Esophagectomy for Postoperative Functional Complaints: A Case Series

open access: yesANZ Journal of Surgery, EarlyView.
Functional complaints affect half of esophagectomy patients, with no standard treatment. In nine patients, Roux‐en‐Y reconstruction for obstruction, redundant conduit, and weight loss was safely performed, with one major complication and no Grade 4 out of five events. Complete symptom resolution reached 67% at 3 months and 89% at 1 year.
Donika Zogaj   +6 more
wiley   +1 more source

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