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Gastroesophageal Reflux Disease

Surgical Clinics of North America, 2011
Millions of Americans are affected by gastroesophageal reflux disease (GERD) in many different ways. The magnitude of the problem of GERD was brought to light by the ambulatory pH test, the introduction of minimally invasive surgery, and the advent of the many medications that are effective in acid suppression.
Alexander S. Rosemurgy   +8 more
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Gastroesophageal Reflux Disease

JAMA, 2020
Gastroesophageal reflux disease (GERD) is defined by recurrent and troublesome heartburn and regurgitation or GERD-specific complications and affects approximately 20% of the adult population in high-income countries.GERD can influence patients' health-related quality of life and is associated with an increased risk of esophagitis, esophageal ...
John Maret-Ouda   +5 more
openaire   +3 more sources

Gastroesophageal Reflux Disease

Medical Clinics of North America, 1991
Gastroesophageal reflux disease, usually manifested by frequent heartburn, occurs in approximately 10% of our adult population. The presence of a hiatal hernia is usually associated with, but does not necessarily cause, LES dysfunction, allowing acid reflux to produce esophageal and aerodigestive symptoms.
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Gastroesophageal Reflux Disease

Scandinavian Journal of Gastroenterology, 1988
In these speculations of the future in gastro-esophageal reflux a hope is expressed that gastro-esophageal reflux disease is accepted as a separate entity. Treatment and diagnosis should not be confused with those of ulcer disease. Reflux disease is not a problem of too much acid in the stomach, but too much acid in the wrong place, the esophagus.
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Gastroesophageal Reflux Disease and Obesity

Gastroenterology Clinics of North America, 2010
Gastroesophageal reflux disease (GERD) is a common condition, with multifactorial pathogenesis, affecting up to 40% of the population. Obesity is also common. Obesity and GERD are clearly related, both from a prevalence and causality association. GERD symptoms increase in severity when people gain weight. Obese patients tend to have more severe erosive
Girish Anand   +2 more
openaire   +4 more sources

Gastroesophageal Reflux Disease

Journal of Clinical Gastroenterology, 2004
Although Galen first described esophagitis almost 2000 years ago, its relation to acid was only recognized in the 19th century by Rokitansky. Considerably more interest in the symptoms and complications of esophagitis has been evident over the last century, as gastroesophageal reflux disease displaced peptic ulceration and became the principal acid ...
Irvin M. Modlin   +3 more
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Prevalence of gastroesophageal reflux disease and gastroesophageal reflux disease symptoms in Japan

Journal of Gastroenterology and Hepatology, 2005
AbstractBackground and Aim:  Epidemiological studies have shown that 10–48% of people in developed countries have gastroesophageal reflux disease (GERD) symptoms such as heartburn and acid regurgitation. The present study aimed to examine the prevalence of GERD symptoms and GERD in Japanese subjects.Methods:  A cross‐sectional study of Japanese ...
Toshio Watanabe   +9 more
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Pathogenesis of gastroesophageal reflux disease

Gastroenterology Clinics of North America, 2002
The pathophysiology of reflux esophagitis involves contact of the esophageal epithelium with acid-pepsin in the refluxate. For this contact to occur with sufficient duration, there must either be a combination of defects in antireflux and luminal clearance mechanisms for acid-pepsin to overwhelm a previously healthy epithelium or primary defects within
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Gastroesophageal Reflux Disease

The American Journal of Nursing, 2000
_ ~~~inappropriately GERD may be unaware of its potential danger. GERD is the most prevalent of the acid-related disorders, which also include dyspepsia, gastritis, and peptic ulcer disease. A cost analysis by Levin and colleagues revealed that the condition is prevalent in 2.9% of HMO patients and leads to an annual cost of $471 per person.
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Gastroesophageal Reflux Disease

Annals of Internal Medicine
Gastroesophageal reflux disease (GERD) is a condition that occurs when reflux of gastric contents into the esophagus causes symptoms and/or complications. The prevalence of GERD in Western societies has been estimated at 30%, making it one of the most commonly encountered disorders in primary care.
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