Results 281 to 290 of about 124,409 (322)

Management of Gastroesophageal Reflux Disease

Gastroenterology, 2018
Management of gastroesophageal reflux disease (GERD) commonly starts with an empiric trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for patients without alarm symptoms. Optimization of therapy (improving compliance and timing of PPI doses), or increasing PPI dosage to twice daily in select circumstances, can reduce ...
C Prakash, Gyawali, Ronnie, Fass
openaire   +3 more sources

GASTROESOPHAGEAL REFLUX DISEASE

Gastroenterology Clinics of North America, 1998
Gastroesophageal reflux disease (GERD) is a spectrum of disease that can best be defined as the symptoms and/or signs of esophageal or adjacent organ injury secondary to the reflux of gastric contents into the esophagus or, beyond, into the oral cavity or airways.
A M, Rai, R C, Orlando
  +12 more sources

Pathophysiology of Gastroesophageal Reflux Disease

World Journal of Surgery, 2017
AbstractGastroesophageal reflux disease pathophysiology is multifactorial and linked to a misbalance between the aggressiveness of the refluxate into the esophagus or adjacent organs and the failure of protective mechanisms associate or not to a defective valvular mechanism at the level of the esophagogastric junction incapable of dealing with a ...
Mariano A, Menezes, Fernando A M, Herbella   +1 more
semanticscholar   +4 more sources

Mechanisms of Gastroesophageal Reflux and Gastroesophageal Reflux Disease

Journal of Pediatric Gastroenterology and Nutrition, 2002
ABSTRACTGastroesophageal reflux is a physiological phenomenon, occurring with different severity and duration in different individuals. Reflux disease occurs when this normal event results in the occurrence of symptoms/signs or complications. The pathophysiology of gastroesophageal reflux is complex and diverse, since it is influenced by factors that ...
Yvan, Vandenplas, Eric, Hassall
openaire   +4 more sources

Gastroesophageal reflux disease

Current Opinion in Internal Medicine, 2003
Globally, gastroesophageal reflux disease (GERD) remains a common and important clinical disorder. This review summarizes the major advances in the understanding and treatment of GERD that have been made in the past 12 months. Epidemiologic studies have yielded additional data on the clinical presentation and natural history of GERD in the East ...
Nguyen, Q., Holloway, R.
openaire   +5 more sources

Gastroesophageal reflux disease

Current Opinion in Gastroenterology, 1999
Gastroesophageal reflux disease is a common clinical problem. Transient lower esophageal sphincter relaxation is central to the pathogenesis. New studies have identified the importance of nitric oxide and cholinergic pathways in modulating transient lower esophageal sphincter relaxation. Provocative information suggests that infection with Helicobacter
openaire   +5 more sources

Endoscopic treatment of proton pump inhibitor‐refractory gastroesophageal reflux disease with anti‐reflux mucosectomy: Experience of 109 cases

Digestive Endoscopy, 2020
Some patients with gastroesophageal reflux disease (GERD) are refractory to proton pump inhibitor (PPI) therapy. Anti‐reflux mucosectomy (ARMS) is a minimally invasive endoscopic procedure for treatment of GERD.
K. Sumi, H. Inoue, Yasutoshi Kobayashi, Yugo Iwaya, Mary Raina Angeli Abad, Y. Fujiyoshi, Y. Shimamura, H. Ikeda, M. Onimaru   +8 more
semanticscholar   +1 more source