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Gastroesophageal Reflux Disease

open access: yesNew England Journal of Medicine, 2023
Symptoms potentially attributable to gastroesophageal reflux disease are among those most commonly reported to primary care providers in the outpatient setting. In this review, we discuss clinical approaches to the evaluation and management of these symptoms, including proton pump inhibitor trials as well as specific indications or clinical settings ...
Wentao, Xu, Xingshun, Qi
semanticscholar   +8 more sources
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GASTROESOPHAGEAL REFLUX DISEASE

Gastroenterology Clinics of North America, 1998
Gastroesophageal reflux disease (GERD) is a spectrum of disease that can best be defined as the symptoms and/or signs of esophageal or adjacent organ injury secondary to the reflux of gastric contents into the esophagus or, beyond, into the oral cavity or airways.
A M, Rai, R C, Orlando
  +12 more sources

Gastroesophageal reflux disease

Current Opinion in Internal Medicine, 2003
Globally, gastroesophageal reflux disease (GERD) remains a common and important clinical disorder. This review summarizes the major advances in the understanding and treatment of GERD that have been made in the past 12 months. Epidemiologic studies have yielded additional data on the clinical presentation and natural history of GERD in the East ...
Nguyen, Q., Holloway, R.
  +8 more sources

Gastroesophageal reflux disease

Current Opinion in Gastroenterology, 1999
Gastroesophageal reflux disease is a common clinical problem. Transient lower esophageal sphincter relaxation is central to the pathogenesis. New studies have identified the importance of nitric oxide and cholinergic pathways in modulating transient lower esophageal sphincter relaxation. Provocative information suggests that infection with Helicobacter
openaire   +5 more sources

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