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Gastroesophageal reflux disease
Postgraduate Medicine, 1989Symptomatic gastroesophageal reflux is one of the most common complaints encountered by clinicians. The pathogenesis of reflux remains unclear, but multiple factors are involved. Heartburn is the most common clinical manifestation. The history and barium esophagram provide sufficient diagnostic information in most cases.
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Pathogenesis of gastroesophageal reflux disease
Gastroenterology Clinics of North America, 2002The pathophysiology of reflux esophagitis involves contact of the esophageal epithelium with acid-pepsin in the refluxate. For this contact to occur with sufficient duration, there must either be a combination of defects in antireflux and luminal clearance mechanisms for acid-pepsin to overwhelm a previously healthy epithelium or primary defects within
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Pathophysiology of Gastroesophageal Reflux Disease.
Gastroenterology, 2017J. Tack, J. Pandolfino
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Management of Gastroesophageal Reflux Disease.
Gastroenterology, 2017P. Gyawali, R. Fass
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