Results 91 to 100 of about 320,864 (335)

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Ultra-early hematoma growth predicts gastrointestinal bleeding after spontaneous intracerebral hemorrhage

Brain Hemorrhages
Objective: Ultra-early hematoma growth (uHG) has been shown to predict hematoma expansion (HE) and poor outcomes in intracerebral hemorrhage (ICH) patients.
Yan Fu, Xiao Hu, Xiao-San Wu, Lei Zhu, Meng-Qiu Zhang, Yun-He Xia, Fang-Jian Zhu, Zi-Jie Wang, Chuan-Qin Fang, Qi Li   +9 more
doaj   +1 more source

Massive Gastrointestinal Bleeding from Choriocarcinoma of the Ovary

Oman Medical Journal, 2018
Choriocarcinoma of the ovary is a rare neoplasm and tends to metastasize early to involve the lungs, brain, and liver. Metastasis to the gastrointestinal tract is rare.
Shiyam Kumar, Zaid R. Raouf, P. A. M. Saparamadu, Ikram A. Burney   +3 more
doaj   +1 more source

Cowden syndrome - Diagnostic skin signs [PDF]

, 2001
Cowden syndrome is a rare autosomal dominant familial cancer syndrome with a high risk of breast cancer. The most important clinical features include carcinomas of the breast and thyroid, and hamartomatous polyps of the gastrointestinal tract.
Burgdorf, Walter H. C., Hildenbrand, C., Lautenschlager, Stephan   +2 more
core   +1 more source

Sindromul Heyde. Stenoza aortică, factor de risc pentru sângerarea gastrointestinală | [Heyde syndrome. Aortic stenosis, risk factor for gastrointestinal bleeding]

, 2021
Constantin Guzgan, Cornelia Zara, H. Rus, Elena Bobescu   +3 more
openalex   +2 more sources

Integrated Microfluidic Platform for High‐Throughput Generation of Intestinal Organoids in Hydrogel Droplets

Advanced Science, EarlyView.
ABSTRACT Organoid research offers valuable insights into human biology and disease, but reproducibility and scalability remain significant challenges, particularly for epithelial organoids. Here, we present an integrated microfluidic platform that addresses these limitations by enabling high‐throughput generation of uniform hydrogel microparticles ...
Barbora Lavickova, Hannah Kronabitter, Mar Cervera‐Negueruela, Eylul Ceylan, Laura Benito‐Zarza, Rubén López‐Sandoval, Irineja Cubela, J. Gray Camp, Jose L. Garcia‐Cordero   +8 more
wiley   +1 more source

Does timing of endoscopy matter for acute upper gastrointestinal bleeding in pediatric portal hypertension? [PDF]

, 2021
Suprabhat Giri, Sridhar Sundaram
openalex   +1 more source

Magnetoelectric Nanotherapy Achieves Complete Tumor Ablation and Prolonged Survival in Pancreatic Cancer Murine Models

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant, Max Shotbolt, Emmanuel Stimphil, Victoria Andre, Elric Zhang, Veronica Estrella, Kazim Husain, Joseph Weygand, Doug Marchion, Alex Sebastian Lopez, Dominique Abrahams, Shawnus Chen, Mostafa Abdel‐Mottaleb, Skye Conlan, Ibrahim Oraiqat, Vaseem Khatri, Jose Alejandro Guevara, Shari Pilon‐Thomas, Gage Redler, Kujtim Latifi, Natarajan Raghunand, Kosj Yamoah, Sarah Hoffe, James Costello, Jessica M. Frakes, Ping Liang, Robert A. Gatenby, Mokenge Malafa, Sakhrat Khizroev   +28 more
wiley   +1 more source

Non-Variceal Upper Gastrointestinal Bleeding [PDF]

The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Non-variceal upper gastrointestinal bleeding (NVUGIB), which predominantly occurs secondary to peptic ulcers, presents a major challenge in emergency departments and is associated with high mortality rates.
Dong Jin Yoon, Joon Sung Kim
doaj   +1 more source

Improved costs and outcomes with conscious sedation vs general anesthesia in TAVR patients: Time to wake up? [PDF]

, 2017
BackgroundTranscatheter aortic valve replacement (TAVR) has become a commonplace procedure for the treatment of aortic stenosis in higher risk surgical patients.
Aksoy, Olcay, Benharash, Peyman, Fernandez, Josue, Johansen, Daniel, Kwon, Murray, Patel, Komal D, Sareh, Sohail, Satou, Nancy, Shemin, Richard J, Suh, William, Toppen, William   +10 more
core   +3 more sources